| Rs10012946
|
| PubMed
|
[PMID 17603484 ]
|
| Affy Probeset
|
SNP_A-2232157
|
| Affy Orientation
|
same
|
| On GW 5.0
|
1
|
| Alleles A/B
|
C/T
|
| Ancestral
|
T
|
| Population
|
Caucasian (UK)
|
| Allele
|
C
|
| Case Freq.
|
|
| Control Freq.
|
|
| Odds Ratio Het
|
|
| Odds Ratio Hom
|
|
| Odds Ratio All
|
1.15
|
| Disease
|
Type II Diabetes (T2D)
|
rs10012946 is in linkage disequilibrium with a polymorphism that increases susceptibility to Type II Diabetes 1.15 times for carriers of the C allele [PMID 17603484]
[PMID 18060660] Testing of diabetes-associated WFS1 polymorphisms in the Diabetes Prevention Program.
[PMID 18426861] Association analysis of type 2 diabetes Loci in type 1 diabetes.
[PMID 18694974] Predicting type 2 diabetes based on polymorphisms from genome-wide association studies: a population-based study.
[PMID 19096518] Novel association of HK1 with glycated hemoglobin in a non-diabetic population: a genome-wide evaluation of 14,618 participants in the Women's Genome Health Study.
[PMID 19341491] Genome-based prediction of common diseases: methodological considerations for future research.
[PMID 20018041] The effect of multiple genetic variants in predicting the risk of type 2 diabetes.
]
