Geno
|
Mag
|
Summary
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(C;C)
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0
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common/normal
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(C;T)
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1.2
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1.2x increased risk for Crohn's disease
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(T;T)
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1.8
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1.8x increased risk for Crohn's disease
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rs10210302 has been reported in a large study to be associated with Crohn's disease.
The risk allele (oriented to the dbSNP entry) is (T); the odds ratio associated with heterozygotes is 1.19 (CI 1.01-1.41), and for homozygotes, 1.85 (CI 1.56-2.21). [PMID 17554300]
OMIM | 611081 |
Desc | INFLAMMATORY BOWEL DISEASE 10; IBD10 |
Variant | |
Related | also |
[PMID 18224312] Pharmacogenetics: data, concepts and tools to improve drug discovery and drug treatment.
[PMID 18438406] Genetic determinants of ulcerative colitis include the ECM1 locus and five loci implicated in Crohn's disease.
[PMID 18533027] Worldwide population differentiation at disease-associated SNPs.
[PMID 20846217] Association of linear growth impairment in pediatric Crohn's disease and a known height locus: a pilot study.
[PMID 25712183] Genetic polymorphism in ATG16L1 gene influences the response to adalimumab in Crohn's disease patients
[PMID 29228965] Genetic polymorphism in ATG16L1 gene is associated with adalimumab use in inflammatory bowel disease.