rs10423928

Orientation

plus

Stabilized

plus

Make rs10423928(A;A)

Make rs10423928(A;T)

Make rs10423928(T;T)

Reference

GRCh38 38.1/141

Chromosome

19

Position

45679046

Gene

GIPR

is a	snp
is	mentioned by
dbSNP	rs10423928
dbSNP (classic)	rs10423928
ClinGen	rs10423928
ebi	rs10423928
HLI	rs10423928
Exac	rs10423928
Gnomad	rs10423928
Varsome	rs10423928
LitVar	rs10423928
Map	rs10423928
PheGenI	rs10423928
Biobank	rs10423928
1000 genomes	rs10423928
hgdp	rs10423928
ensembl	rs10423928
geneview	rs10423928
scholar	rs10423928
google	rs10423928
pharmgkb	rs10423928
gwascentral	rs10423928
openSNP	rs10423928
23andMe	rs10423928
SNPshot	rs10423928
SNPdbe	rs10423928
MSV3d	rs10423928
GWAS Ctlg	rs10423928

GMAF

0.1928

Max Magnitude

0

?	(A;A) (A;T) (T;T)	28

GWAS snp
PMID	[PMID 20081857]
Trait	Two-hour glucose challenge
Title	Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge
Risk Allele	A
P-val	3E-12
Odds Ratio	0.09 [0.07-0.11] mmol/L increase

OMIM	137241
Desc
Variant
Related	also

OMIM	613460
Desc
Variant
Related	also

[PMID 21747410] Association between the GIPR gene and the insulin level after glucose loading in schizophrenia patients treated with olanzapine.

[PMID 21810601] Pleiotropic effects of GIP on islet function involve osteopontin.

[PMID 22399504] Genetic variation in the glucose-dependent insulinotropic polypeptide receptor modifies the association between carbohydrate and fat intake and risk of type 2 diabetes in the Malmo Diet and Cancer cohort.

GWAS snp
PMID	[PMID 23563607]
Trait	Obesity
Title	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.
Risk Allele	T
P-val	4E-13
Odds Ratio	1.16 [NR]

[PMID 23349498] Link between GIP and osteopontin in adipose tissue and insulin resistance.