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rs1052576(A;G)

From SNPedia
0.8x reduced risk of multiple myeloma, general reduced risk of cancer
Is agenotype
ofrs1052576
GeneCASP9
Chromosome1
Position15,506,048
mentionedby
Magnitude1.5
ReputeGood
Geno Mag Summary
(A;A) 1.7 0.5x reduced risk of multiple myeloma, general reduced risk of cancer
(A;G) 1.5 0.8x reduced risk of multiple myeloma, general reduced risk of cancer
(G;G) 1 Increased risk of multiple myeloma, B-cell neoplasms, and cancer in general

A number of studies with lowish p-values but low heterogeneity across studies show a reduced risk of multiple myeloma, greater in homozygotes, for the A allele. There is also a generalized reduction in cancer risk. B-cell neoplasms may be particularly affected.