rs1063856

Orientation

minus

Stabilized

minus

Geno	Mag	Summary
(A;A)	0	common in clinvar

Make rs1063856(A;G)

Make rs1063856(G;G)

Reference

GRCh38 38.1/141

Chromosome

12

Position

6044368

Gene

VWF

is a	snp
is	mentioned by
dbSNP	rs1063856
dbSNP (old)	rs1063856
ClinGen	rs1063856
ebi	rs1063856
HLI	rs1063856
Exac	rs1063856
Gnomad	rs1063856
Varsome	rs1063856
LitVar	rs1063856
Map	rs1063856
PheGenI	rs1063856
Biobank	rs1063856
1000 genomes	rs1063856
hgdp	rs1063856
ensembl	rs1063856
gopubmed	rs1063856
geneview	rs1063856
scholar	rs1063856
google	rs1063856
pharmgkb	rs1063856
gwascentral	rs1063856
openSNP	rs1063856
23andMe	rs1063856
23andMe all	rs1063856
SNPshot	rs1063856
SNPdbe	rs1063856
MSV3d	rs1063856
GWAS Ctlg	rs1063856

GMAF

0.343

Max Magnitude

0

?	(A;A) (A;G) (G;G)	28

[PMID 22133274] Polymorphisms of PAI-1 and platelet GP Ia may associate with impairment of renal function and thrombocytopenia in Puumala hantavirus infection

ClinVar
Risk	rs1063856(C;C) rs1063856(G;G)
Alt	rs1063856(C;C) rs1063856(G;G)
Reference	Rs1063856(A;A)
Significance	Probable-non-pathogenic
Disease	not specified von Willebrand disorder not provided
Variation	info
Gene	VWF
CLNDBN	not specified von Willebrand disorder not provided
Reversed	1
HGVS	NC_000012.11:g.6153534T>C; NC_000012.11:g.6153534T>G
CLNSRC	Academic Unit of Haematology ClinVar
CLNACC	RCV000250620.1, RCV000266084.1, RCV000086605.1,

[PMID 19379518] Development of a fingerprinting panel using medically relevant polymorphisms.

[PMID 20346360] Genetic risk factors for hepatopulmonary syndrome in patients with advanced liver disease.

[PMID 20565774] Population based allele frequencies of disease associated polymorphisms in the Personalized Medicine Research Project.

[PMID 21534939] Genetic variants associated with Von Willebrand factor levels in healthy men and women identified using the HumanCVD BeadChip.

[PMID 22568520] von Willebrand factor plasma levels, genetic variations and coronary heart disease in an older population.

GWAS snp
PMID	[PMID 23267103]
Trait	Coagulation factor levels
Title	Linkage analysis identifies a locus for plasma von Willebrand factor undetected by genome-wide association.
Risk Allele	A
P-val	5E-16
Odds Ratio	.12 [0.091-0.149] lU/dL decrease

[PMID 22858724] IL1B and VWF variants are associated with fibrinolytic early recanalization in patients with ischemic stroke.

[PMID 25779970] Gene-centric approach identifies new and known loci for FVIII activity and VWF antigen levels in European Americans and African Americans