rs11045818
From SNPedia
Orientation | plus |
Stabilized | plus |
Geno | Mag | Summary |
---|---|---|
(G;G) | 0 | common in clinvar |
Make rs11045818(A;A) |
Make rs11045818(A;G) |
Reference | GRCh38.p2 38.2/144 |
Chromosome | 12 |
Position | 21176827 |
Gene | SLCO1B1 |
is a | snp |
is | mentioned by |
dbSNP | rs11045818 |
dbSNP (classic) | rs11045818 |
ClinGen | rs11045818 |
ebi | rs11045818 |
HLI | rs11045818 |
Exac | rs11045818 |
Gnomad | rs11045818 |
Varsome | rs11045818 |
LitVar | rs11045818 |
Map | rs11045818 |
PheGenI | rs11045818 |
Biobank | rs11045818 |
1000 genomes | rs11045818 |
hgdp | rs11045818 |
ensembl | rs11045818 |
geneview | rs11045818 |
scholar | rs11045818 |
rs11045818 | |
pharmgkb | rs11045818 |
gwascentral | rs11045818 |
openSNP | rs11045818 |
23andMe | rs11045818 |
SNPshot | rs11045818 |
SNPdbe | rs11045818 |
MSV3d | rs11045818 |
GWAS Ctlg | rs11045818 |
Max Magnitude | 0 |
? | (A;A) (A;G) (G;G) | 28 |
---|---|---|
|
GWAS snp | |
---|---|
PMID | [PMID 19901119] |
Trait | Methotrexate phramacokinetics (acute lymphoblastic leukemia) |
Title | Germline genetic variation in an organic anion transporter polypeptide associated with methotrexate pharmacokinetics and clinical effects. |
Risk Allele | G |
P-val | 7E-7 |
Odds Ratio | 9.30 [5.7-12.9] mL/min/m2 decrease |
ClinVar | |
---|---|
Risk | rs11045818(A;A) |
Alt | rs11045818(A;A) |
Reference | Rs11045818(G;G) |
Significance | Probable-non-pathogenic |
Disease | Rotor syndrome |
Variation | info |
Gene | SLCO1B1 |
CLNDBN | Rotor syndrome |
Reversed | 0 |
HGVS | NC_000012.11:g.21329761G>A |
CLNSRC | |
CLNACC | RCV000310218.1, |