||1.64x risk for breast cancer
||1.20x risk for breast cancer
|?|| (A;A) (A;G) (G;G) ||28|
This SNP is basically a proxy for SNP rs1219648, which represents the SNP in the FGFR2 gene with the strongest association with breast cancer. [PMID 17529973]
[PMID 18285324] Common variation in the fibroblast growth factor receptor 2 gene is not associated with endometriosis risk.
[PMID 19223389] FGFR2 variants and breast cancer risk: fine-scale mapping using African American studies and analysis of chromatin conformation.
[PMID 19497954] Histone-acetylated control of fibroblast growth factor receptor 2 intron 2 polymorphisms and isoform splicing in breast cancer.
[PMID 19500394] Genetic variants in FGFR2 and FGFR4 genes and skin cancer risk in the Nurses' Health Study.
[PMID 20554749] FGFR2 and other loci identified in genome-wide association studies are associated with breast cancer in African-American and younger women.
[PMID 22965832] Association of common genetic variants with breast cancer risk and clinicopathological characteristics in a Chinese population.
[PMID 23124475] Three novel functional polymorphisms in the promoter of FGFR2 gene and breast cancer risk: a HuGE review and meta-analysis.