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rs114285050

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(A;G) 2 Slightly lower odds of obesity as well as coronary artery disease
(G;G) 0 common/normal


Make rs114285050(A;A)
ReferenceGRCh38.p7 38.3/151
Chromosome5
Position146515831
GeneGPR151
is asnp
is mentioned by
dbSNPrs114285050
dbSNP (old)rs114285050
ClinGenrs114285050
ebirs114285050
HLIrs114285050
Exacrs114285050
Gnomadrs114285050
Varsomers114285050
Maprs114285050
PheGenIrs114285050
Biobankrs114285050
1000 genomesrs114285050
hgdprs114285050
ensemblrs114285050
gopubmedrs114285050
geneviewrs114285050
scholarrs114285050
googlers114285050
pharmgkbrs114285050
gwascentralrs114285050
openSNPrs114285050
23andMers114285050
23andMe allrs114285050
SNPshotrs114285050
SNPdbers114285050
MSV3drs114285050
GWAS Ctlgrs114285050
Max Magnitude2

rs114285050, also known as Arg95Ter or R95X, represents a variant in the GPR151 gene on chromosome 5.

Based on a study of UK BioBank participants, carriers of a rs114285050(A) allele are reported to have 12% lower odds of developing clinical obesity, 14% lower odds of type-2 diabetes (OR 0.86, p=0.006) and 9% lower odds of coronary artery disease (OR 0.91, p=0.01).[PMID 29691411]