rs11571746

plus

Geno	Mag	Summary
(C;C)	2
(C;T)	1	Benign or at worst a very minor risk factor
(T;T)	0	common in complete genomics

Reference

GRCh38 38.1/141

Chromosome

13

Position

32370971

Gene

BRCA2

is a	snp
is	mentioned by
dbSNP	rs11571746
dbSNP (classic)	rs11571746
ClinGen	rs11571746
ebi	rs11571746
HLI	rs11571746
Exac	rs11571746
Gnomad	rs11571746
Varsome	rs11571746
LitVar	rs11571746
Map	rs11571746
PheGenI	rs11571746
Biobank	rs11571746
1000 genomes	rs11571746
hgdp	rs11571746
ensembl	rs11571746
geneview	rs11571746
scholar	rs11571746
google	rs11571746
pharmgkb	rs11571746
gwascentral	rs11571746
openSNP	rs11571746
23andMe	rs11571746
SNPshot	rs11571746
SNPdbe	rs11571746
MSV3d	rs11571746
GWAS Ctlg	rs11571746

GMAF

0.0009183

Max Magnitude

2

aka c.8503T>C (p.Ser2835Pro)

?

(C;C) (C;T) (T;T)

28

This SNP, a variant in the BRCA2 gene, is 1 of 25 SNPs reported to represent independently minor, but cumulatively significant, increased risk for breast cancer. [PMID 17341484]

For details of all 25 SNPs in this group, along with the two methods used to calculate overall risk estimates for breast cancer, refer to the SNPedia breast cancer entry.

For this particular SNP, the risk (minor) allele is (C).

23andMe name: i5009299

ClinVar
Risk	Rs11571746(C;C)
Alt	Rs11571746(C;C)
Reference	Rs11571746(T;T)
Significance	Other
Disease	Breast-ovarian cancer not specified Hereditary cancer-predisposing syndrome Hereditary breast and ovarian cancer syndrome
Variation	info
Gene	BRCA2
CLNDBN	Breast-ovarian cancer, familial 2 not specified Hereditary cancer-predisposing syndrome Hereditary breast and ovarian cancer syndrome
Reversed	0
HGVS	NC_000013.10:g.32945108T>C
CLNSRC	Ambry Genetics ClinVar Counsyl GeneDx
CLNACC	RCV000113950.4, RCV000120364.6, RCV000129146.2, RCV000167840.7,