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rs12467557

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(A;A) 0 common in complete genomics
Make rs12467557(A;G)
Make rs12467557(G;G)
ReferenceGRCh38 38.1/141
Chromosome2
Position51015132
GeneNRXN1
is asnp
is mentioned by
dbSNPrs12467557
dbSNP (classic)rs12467557
ClinGenrs12467557
ebirs12467557
HLIrs12467557
Exacrs12467557
Gnomadrs12467557
Varsomers12467557
LitVarrs12467557
Maprs12467557
PheGenIrs12467557
Biobankrs12467557
1000 genomesrs12467557
hgdprs12467557
ensemblrs12467557
geneviewrs12467557
scholarrs12467557
googlers12467557
pharmgkbrs12467557
gwascentralrs12467557
openSNPrs12467557
23andMers12467557
SNPshotrs12467557
SNPdbers12467557
MSV3drs12467557
GWAS Ctlgrs12467557
GMAF0.1915
Max Magnitude0
? (A;A) (A;G) (G;G) 28


rs12467557 increases susceptibility to Substance dependence, Nicotine 1.81 times for carriers of the C allele [PMID 17158188OA-icon.png]


[PMID 18270208OA-icon.png] Significant association of the neurexin-1 gene (NRXN1) with nicotine dependence in European- and African-American smokers.


[PMID 20860064] Influence of neurexin 1 (NRXN1) polymorphisms in clozapine response.