rs12704795
From SNPedia
| Orientation | plus |
| Stabilized | plus |
| Make rs12704795(G;G) |
| Make rs12704795(G;T) |
| Make rs12704795(T;T) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 7 |
| Position | 95424695 |
| Gene | PON2 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs12704795 |
| dbSNP (classic) | rs12704795 |
| ClinGen | rs12704795 |
| ebi | rs12704795 |
| HLI | rs12704795 |
| Exac | rs12704795 |
| Gnomad | rs12704795 |
| Varsome | rs12704795 |
| LitVar | rs12704795 |
| Map | rs12704795 |
| PheGenI | rs12704795 |
| Biobank | rs12704795 |
| 1000 genomes | rs12704795 |
| hgdp | rs12704795 |
| ensembl | rs12704795 |
| geneview | rs12704795 |
| scholar | rs12704795 |
| rs12704795 | |
| pharmgkb | rs12704795 |
| gwascentral | rs12704795 |
| openSNP | rs12704795 |
| 23andMe | rs12704795 |
| SNPshot | rs12704795 |
| SNPdbe | rs12704795 |
| MSV3d | rs12704795 |
| GWAS Ctlg | rs12704795 |
| Merged from | Rs17876088 |
| GMAF | 0.225 |
| Max Magnitude | 0 |
According to [PMID 16822964], variations at rs12704795, originally known as rs17876088, located in an intron of the PON2 gene, appear to modulate both susceptibility to, and protection from, the sporadic form of ALS (Lou Gehrig's disease).
[PMID 17096118] Paraoxonase 2 (PON2) polymorphisms and development of renal dysfunction in type 2 diabetes: UKPDS 76.
[PMID 19546579
] Evaluation of polymorphisms in paraoxonase 2 (PON2) gene and their association with cardiovascular-renal disease risk in Mexican Americans.
[PMID 21223581] Association analysis of PON2 genetic variants with serum paraoxonase activity and systemic lupus erythematosus.
