Geno
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Mag
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Summary
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(C;T)
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4.9
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Short sleeper; rare mutation reported to reduce sleep time needed
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(T;T)
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0
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common/normal; 8+ hours of sleep typically needed
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rs1406844918 represents a rare mutation known as the Y206H (p.Tyr206His) mutation in the neuropeptide S receptor 1 NPSR1 gene, located on chromosome 7.
In 2019, a report was published indicating this mutation was responsible for the short sleep phenotype observed in a (single) Chinese family. It is apparently a gain-of-function mutation and thus able to be inherited in a dominant manner. People with this trait [familial natural short sleep (FNSS)] have a lifelong tendency to sleep only 4 to 6 hours per night while still feeling sufficiently rested.[PMID 31619542]