Have questions? Visit https://www.reddit.com/r/SNPedia

rs150090666

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(C;C) 0 common/normal
(C;T) 1.5 Slightly lower odds of developing hypercholesterolemia
Make rs150090666(T;T)
ReferenceGRCh38.p7 38.3/151
Chromosome11
Position14843853
GenePDE3B
is asnp
is mentioned by
dbSNPrs150090666
dbSNP (old)rs150090666
ClinGenrs150090666
ebirs150090666
HLIrs150090666
Exacrs150090666
Gnomadrs150090666
Varsomers150090666
LitVarrs150090666
Maprs150090666
PheGenIrs150090666
Biobankrs150090666
1000 genomesrs150090666
hgdprs150090666
ensemblrs150090666
gopubmedrs150090666
geneviewrs150090666
scholarrs150090666
googlers150090666
pharmgkbrs150090666
gwascentralrs150090666
openSNPrs150090666
23andMers150090666
23andMe allrs150090666
SNPshotrs150090666
SNPdbers150090666
MSV3drs150090666
GWAS Ctlgrs150090666
Max Magnitude1.5

rs150090666, also known as p.Arg783Ter or R783X, represents a variant in the PDE3B gene on chromosome 11.

Based on a study of UK BioBank participants, carriers of a rs150090666(T) allele are reported to be less likely to be diagnosed with hypercholesterolemia (OR 0.52, p=0.0002) and they are also likely to have a slightly lower body mass index compared to non-carriers.[PMID 29691411]