|(A;A)||Higher BMI than normal|
|(A;T)||Higher BMI than normal|
|Title||NRXN3 Is a Novel Locus for Waist Circumference: A Genome-Wide Association Study from the CHARGE Consortium|
|Odds Ratio||NR NR|
[PMID 20075932] Association of gene polymorphism of the fat-mass and obesity-associated gene with insulin resistance in Japanese
|Title||Two new loci for body-weight regulation identified in a joint analysis of genome-wide association studies for early-onset extreme obesity in French and German study groups|
|Odds Ratio||1.37 [1.26-1.50]|
|Title||Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index|
|Odds Ratio||0.39 [0.35-0.43] kg/m2 increase|
[PMID 21443588] Association between the FTO gene and overweight in Japanese children and adolescents
|Title||Replication of 13 obesity loci among Singaporean Chinese, Malay and Asian-Indian populations.|
|Odds Ratio||0.0900 [0.06-0.12] unit decrease|
[PMID 21796137] Association of variations in the FTO, SCG3 and MTMR9 genes with metabolic syndrome in a Japanese population
[PMID 22235250] Quantile-specific penetrance of genes affecting lipoproteins, adiposity and height
[PMID 22589738] Genome-Wide Association for Abdominal Subcutaneous and Visceral Adipose Reveals a Novel Locus for Visceral Fat in Women
[PMID 18379722] Variations in the FTO gene are associated with severe obesity in the Japanese.
[PMID 20703240] Polymorphisms in NRXN3, TFAP2B, MSRA, LYPLAL1, FTO and MC4R and their effect on visceral fat area in the Japanese population.
[PMID 22041983] Recapitulation of genome-wide association studies on body mass index in the Korean population.
[PMID 22222230] FTO gene polymorphisms and platelet counts in a general Japanese population.
[PMID 22504289] FTO, Abdominal Adiposity, Fasting Hyperglycemia Associated with Elevated HbA1c in Japanese Middle-Aged Women.
[PMID 23254338] FTO First Intron rs1558902 Variant and Platelets Count in White Middle-aged Women: Prague Pre and Post Menopausal Females (3PMFs) Study
[PMID 24084939] A common biological basis of obesity and nicotine addiction
[PMID 24106974] Association between fat mass and obesity-associated (FTO) gene and hip fracture susceptibility
|Title||Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.|
|Odds Ratio||1.14 [NR]|
[PMID 22891219] FTO genotype and 2-year change in body composition and fat distribution in response to weight-loss diets: the POUNDS LOST Trial.
[PMID 23471855] The genetics of childhood obesity and interaction with dietary macronutrients.
[PMID 24911064] Association of FTO Polymorphisms with Obesity and Metabolic Parameters in Han Chinese Adolescents
[PMID 24983943] Effects of BMI, Fat Mass, and Lean Mass on Asthma in Childhood: A Mendelian Randomization Study
[PMID 25091360] Fat-mass and obesity-associated gene variant and changes of body mass index from ages 3 to 13 years
|Trait||Body mass index|
|Title||Meta-analysis of genome-wide association studies in East Asian-ancestry populations identifies four new loci for body mass index.|
|Odds Ratio||.08 [0.062-0.089] unit increase|
[PMID 25761503] Dietary Fat Modifies the Effects of FTO Genotype on Changes in Insulin Sensitivity
[PMID 27820839] FTO Gene Polymorphism Is Associated with Type 2 Diabetes through Its Effect on Increasing the Maximum BMI in Japanese Men.
[PMID 28528403] Assessing the causal relationship between obesity and venous thromboembolism through a Mendelian Randomization study.
[PMID 29212175] The role of established East Asian obesity-related loci on pediatric leptin levels highlights a neuronal influence on body weight regulation in Chinese children and adolescents: the BCAMS study.
[PMID 29548861] Familial aggregation and linkage analysis with covariates for metabolic syndrome risk factors.