rs1678542
Orientation | minus |
Stabilized | minus |
Make rs1678542(C;C) |
Make rs1678542(C;G) |
Make rs1678542(G;G) |
Reference | GRCh38 38.1/141 |
Chromosome | 12 |
Position | 57574932 |
Gene | KIF5A |
is a | snp |
is | mentioned by |
dbSNP | rs1678542 |
dbSNP (classic) | rs1678542 |
ClinGen | rs1678542 |
ebi | rs1678542 |
HLI | rs1678542 |
Exac | rs1678542 |
Gnomad | rs1678542 |
Varsome | rs1678542 |
LitVar | rs1678542 |
Map | rs1678542 |
PheGenI | rs1678542 |
Biobank | rs1678542 |
1000 genomes | rs1678542 |
hgdp | rs1678542 |
ensembl | rs1678542 |
geneview | rs1678542 |
scholar | rs1678542 |
rs1678542 | |
pharmgkb | rs1678542 |
gwascentral | rs1678542 |
openSNP | rs1678542 |
23andMe | rs1678542 |
SNPshot | rs1678542 |
SNPdbe | rs1678542 |
MSV3d | rs1678542 |
GWAS Ctlg | rs1678542 |
GMAF | 0.4793 |
Max Magnitude | 0 |
? | (C;C) (C;G) (G;G) | 28 |
---|---|---|
|
GWAS | |
---|---|
SNP | rs1678542 |
PubMedID | [PMID 18794853] |
Condition | Rheumatoid arthritis |
Gene | KIF5A-PIP4K2C |
Risk Allele | C |
pValue | 9.00E-008 |
OR | 1.12 |
95% CI |
[PMID 19956108] Analysis of 55 autoimmune disease and type II diabetes loci: further confirmation of chromosomes 4q27, 12q13.2 and 12q24.13 as type I diabetes loci, and support for a new locus, 12q13.3-q14.1
[PMID 20508602] The autoimmune disease-associated KIF5A, CD226 and SH2B3 gene variants confer susceptibility for multiple sclerosis
[PMID 20498205] Investigation of potential non-HLA rheumatoid arthritis susceptibility loci in a European cohort increases the evidence for nine markers
[PMID 19674979] Overlap of disease susceptibility loci for rheumatoid arthritis and juvenile idiopathic arthritis.
[PMID 20439292] Genetic variants in the prediction of rheumatoid arthritis.
[PMID 20444755] Investigation of rheumatoid arthritis susceptibility genes identifies association of AFF3 and CD226 variants with response to anti-tumour necrosis factor treatment.
[PMID 23378462] Replication of European Rheumatoid Arthritis Loci in a Pakistani Population
[PMID 22328738] Comprehensive assessment of rheumatoid arthritis susceptibility loci in a large psoriatic arthritis cohort.
GWAS snp | |
---|---|
PMID | [PMID 24449572] |
Trait | Rheumatoid arthritis |
Title | Novel rheumatoid arthritis susceptibility locus at 22q12 identified in an extended UK genome-wide association study. |
Risk Allele | |
P-val | 1E-7 |
Odds Ratio | 1.20 [1.12-1.28] |
[PMID 26092158] IRF5, PTPN22, CD28, IL2RA, KIF5A, BLK and TNFAIP3 genes polymorphisms and lupus susceptibility in a cohort from the Egypt Delta; relation to other ethnic groups