rs17110563
From SNPedia
| Orientation | plus |
| Stabilized | plus |
| Geno | Mag | Summary |
|---|---|---|
| (C;C) | 0 | common in complete genomics |
| Make rs17110563(C;T) |
| Make rs17110563(T;T) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 12 |
| Position | 71972526 |
| Gene | TPH2 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs17110563 |
| dbSNP (classic) | rs17110563 |
| ClinGen | rs17110563 |
| ebi | rs17110563 |
| HLI | rs17110563 |
| Exac | rs17110563 |
| Gnomad | rs17110563 |
| Varsome | rs17110563 |
| LitVar | rs17110563 |
| Map | rs17110563 |
| PheGenI | rs17110563 |
| Biobank | rs17110563 |
| 1000 genomes | rs17110563 |
| hgdp | rs17110563 |
| ensembl | rs17110563 |
| geneview | rs17110563 |
| scholar | rs17110563 |
| rs17110563 | |
| pharmgkb | rs17110563 |
| gwascentral | rs17110563 |
| openSNP | rs17110563 |
| 23andMe | rs17110563 |
| SNPshot | rs17110563 |
| SNPdbe | rs17110563 |
| MSV3d | rs17110563 |
| GWAS Ctlg | rs17110563 |
| Max Magnitude | 0 |
| ? | (C;C) (C;T) (T;T) | 28 |
|---|---|---|
|
| ||
rs17110563, also known as Pro206Ser, is a SNP in the TPH2 gene. The minor allele of this SNP yielded an odds ratio of 4.8 (CI:1.6-14.8) for increased risk for bipolar disorder in a study of 883 Russian patients.[PMID 17905754]
| ClinVar | |
|---|---|
| Risk | rs17110563(T;T) |
| Alt | rs17110563(T;T) |
| Reference | Rs17110563(C;C) |
| Significance | Other |
| Disease | Bipolar affective disorder |
| Variation | info |
| Gene | TPH2 |
| CLNDBN | Bipolar affective disorder, susceptibility to |
| Reversed | 0 |
| HGVS | NC_000012.11:g.72366306C>T |
| CLNSRC | OMIM Allelic Variant UniProtKB (protein) |
| CLNACC | RCV000003314.2, |
[PMID 18797398] Investigation of the tryptophan hydroxylase 2 gene in bipolar I disorder in the Romanian population.
