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rs1800566(C;T)

From SNPedia
Possible Lower Lung Cancer risk
Is agenotype
ofrs1800566
GeneNQO1
Chromosome16
Position69,711,242
mentionedby
Magnitude1.8
ReputeGood
Geno Mag Summary
(C;C) 0 common in clinvar
(C;T) 1.8 Possible Lower Lung Cancer risk
(T;T) 3.1 Benzene toxicity; cancer risks

rs1800566 may decrease susceptibility to Lung Cancer 0.48 times for heterozygotes (CT) due to the presence of the T allele reducing the rate at which the pro-carcinogenic activating NOD1 enzyme operates [PMID 15498787]