rs1800955
| influences personality |
| Orientation | plus |
| Stabilized | plus |
| Geno | Mag | Summary |
|---|---|---|
| (C;C) | 2 | increased susceptibility to novelty seeking |
| (C;T) | 2 | increased susceptibility to novelty seeking |
| (T;T) | 0 | normal |
| Reference | GRCh37 37.1/131 |
| Chromosome | 11 |
| Position | 636784 |
| Gene | DRD4 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs1800955 |
| dbSNP (classic) | rs1800955 |
| ClinGen | rs1800955 |
| ebi | rs1800955 |
| HLI | rs1800955 |
| Exac | rs1800955 |
| Gnomad | rs1800955 |
| Varsome | rs1800955 |
| LitVar | rs1800955 |
| Map | rs1800955 |
| PheGenI | rs1800955 |
| Biobank | rs1800955 |
| 1000 genomes | rs1800955 |
| hgdp | rs1800955 |
| ensembl | rs1800955 |
| geneview | rs1800955 |
| scholar | rs1800955 |
| rs1800955 | |
| pharmgkb | rs1800955 |
| gwascentral | rs1800955 |
| openSNP | rs1800955 |
| 23andMe | rs1800955 |
| SNPshot | rs1800955 |
| SNPdbe | rs1800955 |
| MSV3d | rs1800955 |
| GWAS Ctlg | rs1800955 |
| GMAF | 0.3742 |
| Max Magnitude | 2 |
rs1800955, also known as C-521T and -521C/T, is a variant in the promoter region upstream of the DRD4 gene on chromosome 11.
g2b2mh blog C allele of rs1800955 DRD4 gene 10.1016/j.biopsych.2007.04.006 survives an analysis of several dozen studies on genetics and personality. Although small, the evidence from the final meta-analysis indicates that the C-521T may account for up to 3% of phenotypic variance. [PMID 17574217]
rs1800955 and rs1800443 are discussed in this article in the Atlantic Magazine as influencing personality.
[PMID 25010186
] Dissociable Genetic Contributions to Error Processing: A Multimodal Neuroimaging Study
[PMID 24691022] Variants in the Dopamine-4-Receptor Gene Promoter Are Not Associated with Sensation Seeking in Skiers
[PMID 24100617] Genetic modulation of personality traits: a systematic review of the literature.
[PMID 23840506] Multivariate analysis of dopaminergic gene variants as risk factors of heroin dependence
[PMID 23252368] The -521 C/T variant in the dopamine-4-receptor gene (DRD4) is associated with skiing and snowboarding behavior
[PMID 23031802] Do SNPs of DRD4 gene predict adult persistence of ADHD in a Chinese sample?
[PMID 22530780] Impact of five SNPs in dopamine-related genes on executive function.
[PMID 20468066] The DRD4 receptor Exon 3 VNTR and 5' SNP variants and mRNA expression in human post-mortem brain tissue
[PMID 20205808] Association between dopaminergic polymorphisms and borderline personality traits among at-risk young adults and psychiatric inpatients.
[PMID 21609749] Role of functional dopaminergic gene polymorphisms in the etiology of idiopathic intellectual disability.
[PMID 21216270] Role of gene-gene/gene-environment interaction in the etiology of eastern Indian ADHD probands.
[PMID 20191112] The Genetics of Anorexia Nervosa: Current Findings and Future Perspectives.
[PMID 20046399] Genetic polymorphisms in dopamine- and serotonin-related genes and treatment responses to risperidone and perospirone
[PMID 19911060] Persistence criteria for susceptibility genes for schizophrenia: a discussion from an evolutionary viewpoint.
[PMID 19258022] Now or Later? An fMRI study of the effects of endogenous opioid blockade on a decision-making network.
[PMID 18715757] Genetic associations with schizophrenia: meta-analyses of 12 candidate genes.
[PMID 17089069] Association and synergistic interaction between promoter variants of the DRD4 gene in Japanese schizophrenics.
