rs180177136

Orientation

minus

Stabilized

minus

Geno	Mag	Summary
(A;A)	0	common in clinvar
(A;G)	3	2-4 fold higher risk for breast cancer, depending on family history
(G;G)	7	Fanconi anemia, complementation group N

Reference

GRCh38 38.1/141

Chromosome

16

Position

23607860

Gene

PALB2

is a	snp
is	mentioned by
dbSNP	rs180177136
dbSNP (classic)	rs180177136
ClinGen	rs180177136
ebi	rs180177136
HLI	rs180177136
Exac	rs180177136
Gnomad	rs180177136
Varsome	rs180177136
LitVar	rs180177136
Map	rs180177136
PheGenI	rs180177136
Biobank	rs180177136
1000 genomes	rs180177136
hgdp	rs180177136
ensembl	rs180177136
geneview	rs180177136
scholar	rs180177136
google	rs180177136
pharmgkb	rs180177136
gwascentral	rs180177136
openSNP	rs180177136
23andMe	rs180177136
SNPshot	rs180177136
SNPdbe	rs180177136
MSV3d	rs180177136
GWAS Ctlg	rs180177136

Max Magnitude

7

ClinVar
Risk	Rs180177136(G;G)
Alt	Rs180177136(G;G)
Reference	Rs180177136(A;A)
Significance	Other
Disease	Familial cancer of breast Fanconi anemia Hereditary cancer-predisposing syndrome not provided
Variation	info
Gene	PALB2
CLNDBN	Familial cancer of breast Fanconi anemia, complementation group N Hereditary cancer-predisposing syndrome not provided
Reversed	1
HGVS	NC_000016.9:g.23619181T>C
CLNSRC	PALB2 database
CLNACC	RCV000114621.1, RCV000114622.1, RCV000213830.1, RCV000433683.1,

[PMID 17200671] Biallelic mutations in PALB2 cause Fanconi anemia subtype FA-N and predispose to childhood cancer.