|(A;A)||increased risk for Crohn's disease|
|(G;G)||0.72x decreased risk for Crohn's disease|
|?||(A;A) (A;G) (G;G)||28|
rs1992660 is a SNP upstream of the PTGER4 gene that was found in a genome-wide association study to be associated with Crohn's disease.
In several European populations, the most common allele, rs1992660(A), was associated with increased risk for Crohn's disease. Conversely, the odds ratio (pooled over several populations) for the minor allele, rs1992660(G), was 0.72 (CI: 0.60-0.86, p=0.0005).[PMID 17684544]
|Condition||Irritable bowel syndrome|