23andMe blog psoriasis
Europeans
GWAS snp
|
PMID
|
[PMID 19169254]
|
Trait
|
Psoriasis
|
Title
|
Genome-wide scan reveals association of psoriasis with IL-23 and NF-kappaB pathways
|
Risk Allele
|
A
|
P-val
|
1E-9
|
Odds Ratio
|
1.34 None
|
GWAS snp
|
PMID
|
[PMID 20953190]
|
Trait
|
|
Title
|
A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1
|
Risk Allele
|
|
P-val
|
2E-7
|
Odds Ratio
|
1.4900 [1.28-1.73]
|
[PMID 21623003] Confirmation of TNIP1 and IL23A as susceptibility loci for psoriatic arthritis
[PMID 20154336] Comprehensive sequence analysis of the human IL23A gene defines new variation content and high rate of evolutionary conservation.
[PMID 21253569] Genome-wide association study SNPs in the human genome diversity project populations: does selection affect unlinked SNPs with shared trait associations?
[PMID 23579029] Protective effect of interleukin-23A (IL23A) haplotype variants on type 1A diabetes mellitus in a Brazilian population
[PMID 23673284] Association study in Romanians confirms IL23A gene haplotype block rs2066808/rs11171806 as conferring risk to psoriatic arthritis
[PMID 24957500] Genetic variation at IL12B, IL23R and IL23A is associated with psoriasis severity, psoriatic arthritis and type 2 diabetes mellitus
[PMID 27893410] Characterization of variations in IL23A and IL23R genes: possible roles in multiple sclerosis and other neuroinflammatory demyelinating diseases.