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rs2153157

From SNPedia

Orientationminus
Stabilizedminus
Make rs2153157(C;C)
Make rs2153157(C;T)
Make rs2153157(T;T)
ReferenceGRCh38 38.1/141
Chromosome6
Position10897255
GeneSYCP2L
is asnp
is mentioned by
dbSNPrs2153157
dbSNP (classic)rs2153157
ClinGenrs2153157
ebirs2153157
HLIrs2153157
Exacrs2153157
Gnomadrs2153157
Varsomers2153157
LitVarrs2153157
Maprs2153157
PheGenIrs2153157
Biobankrs2153157
1000 genomesrs2153157
hgdprs2153157
ensemblrs2153157
geneviewrs2153157
scholarrs2153157
googlers2153157
pharmgkbrs2153157
gwascentralrs2153157
openSNPrs2153157
23andMers2153157
SNPshotrs2153157
SNPdbers2153157
MSV3drs2153157
GWAS Ctlgrs2153157
GMAF0.3985
Max Magnitude0
? (C;C) (C;T) (T;T) 28


23andMe blog rs2153157(A) Menopause about 15 weeks later

GWAS snp
PMID [PMID 19448621OA-icon.png]
Trait Menarche and menopause (age at onset)
Title Genome-wide association studies identify loci associated with age at menarche and age at natural menopause
Risk Allele T
P-val 5E-8
Odds Ratio 0.29 [0.19-0.39] years older
OMIM300488
DescMENOPAUSE, NATURAL, AGE AT, QUANTITATIVE TRAIT LOCUS 1; MENOQ1
Variant
Relatedalso
GWAS snp
PMID [PMID 22267201OA-icon.png]
Trait
Title Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways.
Risk Allele A
P-val 8E-12
Odds Ratio 0.1650 None



[PMID 23508249OA-icon.png] Replication of genetic loci for ages at menarche and menopause in the multi-ethnic Population Architecture using Genomics and Epidemiology (PAGE) study


[PMID 23592221] Shared genetic factors for age at natural menopause in Iranian and European women


[PMID 23307926OA-icon.png] A genome-wide association study of early menopause and the combined impact of identified variants.