rs2229774(C;T)
From SNPedia
| higher risk for anthracycline side-effects for childhood cancer patients |
| Is a | genotype |
| of | rs2229774 |
| Gene | RARG |
| Chromosome | 12 |
| Position | 53,211,761 |
| mentioned | by |
| Magnitude | 3 |
| Repute | Bad |
| Geno | Mag | Summary |
|---|---|---|
| (C;C) | 0 | common/normal |
| (C;T) | 3 | higher risk for anthracycline side-effects for childhood cancer patients |
~5x higher risk of cardiotoxicity from anthracycline when used to treat childhood cancers; see discussion at rs2229774
