Rs224136
|
PubMed
|
[PMID 17435756]
|
Affy Probeset
|
SNP_A-1883807
|
Affy Orientation
|
reverse
|
On GW 5.0
|
1
|
Alleles A/B
|
A/G
|
Ancestral
|
T
|
Population
|
EU
|
Allele
|
C
|
Case Freq.
|
0.87
|
Control Freq.
|
0.81
|
Odds Ratio Het
|
|
Odds Ratio Hom
|
|
Odds Ratio All
|
1.67
|
Disease
|
Crohn's disease (CD)
|
Carriers of the C allele of rs224136 reportedly have 1.67 times higher susceptibility to Crohn's disease. [PMID 17435756]
Rs224136 is not a major genetic risk factor for susceptibility to Crohn's disease in the German population. [PMID 19262523]
OMIM | 612255 |
Desc | INFLAMMATORY BOWEL DISEASE 15; IBD15 |
Variant | |
Related | also |
[PMID 17068223] A genome-wide association study identifies IL23R as an inflammatory bowel disease gene.
[PMID 20195480] The cannabinoid 1 receptor (CNR1) 1359 G/A polymorphism modulates susceptibility to ulcerative colitis and the phenotype in Crohn's disease.
[PMID 20222171] T300A polymorphism of ATG16L1 and susceptibility to inflammatory bowel diseases: a meta-analysis.