| Geno
|
Mag
|
Summary
|
| (C;C)
|
0
|
normal
|
| (C;T)
|
|
higher transferrin levels if rs1800562(A;A)
|
| (T;T)
|
|
higher transferrin levels if rs1800562(A;A)
|
rs235756, a relatively common SNP in the BMP2 gene, has been associated with higher serum transferrin levels - and presumably therefore higher risk for developing hemochromatosis - in the rare individuals who are rs1800562(A;A) homozygotes, i.e. those known as C282Y homozygotes.[PMID 17847004
]
[PMID 21515830] Genetic variations in the transforming growth factor beta pathway as predictors of survival in advanced non-small cell lung cancer
[PMID 19673882] A novel association between a SNP in CYBRD1 and serum ferritin levels in a cohort study of HFE hereditary haemochromatosis.
[PMID 19879168] A common SNP near BMP2 is associated with severity of the iron burden in HFE p.C282Y homozygous patients: a follow-up study.
[PMID 22323359] TMPRSS6, but not TF, TFR2 or BMP2 variants are associated with increased risk of iron-deficiency anemia.
[PMID 28151393] Genetic factors associated with iron storage in Australian blood donors.
]
