|?|| (A;A) (A;G) (G;G) ||28|
rs2398162 has been reported in a large study to be associated with high blood pressure.
The risk allele (oriented to the dbSNP entry) is (A); the odds ratio associated with heterozygotes is 0.97 (CI 0.76-1.25), and for homozygotes, 1.31 (CI 1.03-1.67). [PMID 17554300]
[PMID 18523456] Replication of the Wellcome Trust genome-wide association study of essential hypertension: the Family Blood Pressure Program.
[PMID 20018036] Using a latent growth curve model for an integrative assessment of the effects of genetic and environmental factors on multiple phenotypes.
[PMID 21228780] Novel genetic variations associated with salt sensitivity in the Korean population.