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rs2450115

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(T;T) 0 common/normal
Make rs2450115(C;C)
Make rs2450115(C;T)
ReferenceGRCh38.p7 38.3/150
Chromosome8
Position116611854
GeneLOC105375712
is asnp
is mentioned by
dbSNPrs2450115
dbSNP (old)rs2450115
ClinGenrs2450115
ebirs2450115
HLIrs2450115
Exacrs2450115
Gnomadrs2450115
Varsomers2450115
LitVarrs2450115
Maprs2450115
PheGenIrs2450115
Biobankrs2450115
1000 genomesrs2450115
hgdprs2450115
ensemblrs2450115
gopubmedrs2450115
geneviewrs2450115
scholarrs2450115
googlers2450115
pharmgkbrs2450115
gwascentralrs2450115
openSNPrs2450115
23andMers2450115
23andMe allrs2450115
SNPshotrs2450115
SNPdbers2450115
MSV3drs2450115
GWAS Ctlgrs2450115
Max Magnitude0

Colorectal Cancer Risk:

A large GWAS study of ~20,000 East-Asians identified 4 loci associated with a small increase (10%-18% increase) in CRC risk per allele: P values for the most significant variant in each locus ranged from 3.92 × 10(-8) to 1.24 × 10(-12): 6p21.1 (rs4711689), 8q23.3 (rs2450115, rs6469656), 10q24.3 (rs4919687), and 12p13.3 (rs11064437).[PMID 26965516OA-icon.png]