rs261332
From SNPedia
Orientation | plus |
Stabilized | plus |
Geno | Mag | Summary |
---|---|---|
(A;A) | 2 | associated with higher HDL cholesterol |
(A;G) | 2 | associated with higher HDL cholesterol |
(G;G) | 0 | common in complete genomics |
Reference | GRCh38 38.1/141 |
Chromosome | 15 |
Position | 58435126 |
Gene | LIPC, LIPC-AS1 |
is a | snp |
is | mentioned by |
dbSNP | rs261332 |
dbSNP (classic) | rs261332 |
ClinGen | rs261332 |
ebi | rs261332 |
HLI | rs261332 |
Exac | rs261332 |
Gnomad | rs261332 |
Varsome | rs261332 |
LitVar | rs261332 |
Map | rs261332 |
PheGenI | rs261332 |
Biobank | rs261332 |
1000 genomes | rs261332 |
hgdp | rs261332 |
ensembl | rs261332 |
geneview | rs261332 |
scholar | rs261332 |
rs261332 | |
pharmgkb | rs261332 |
gwascentral | rs261332 |
openSNP | rs261332 |
23andMe | rs261332 |
SNPshot | rs261332 |
SNPdbe | rs261332 |
MSV3d | rs261332 |
GWAS Ctlg | rs261332 |
GMAF | 0.1924 |
Max Magnitude | 2 |
? | (A;A) (A;G) (G;G) | 28 |
---|---|---|
|
Rs261332 | |
---|---|
PubMed | [PMID 17463246] |
Affy Probeset | SNP_A-4301630 |
Affy Orientation | reverse |
On GW 5.0 | 1 |
Alleles A/B | C/T |
Ancestral | |
Population | NEU |
Allele | A |
Case Freq. | |
Control Freq. | 0.18 |
Odds Ratio Het | |
Odds Ratio Hom | |
Odds Ratio All | - |
Disease | Elevated HDL-Cholesterol (E-HDL) |
rs261332 increases susceptibility to Elevated HDL-Cholesterol for carriers of the A allele [PMID 17463246]
A allele is associated with 1.41mg/dl increase in HDL cholesterol (good cholesterol). [PMID 18193043]
[PMID 18179892] Genome-wide association study identifies genes for biomarkers of cardiovascular disease: serum urate and dyslipidemia.
[PMID 19041386] Genetic-epidemiological evidence on genes associated with HDL cholesterol levels: a systematic in-depth review.
[PMID 19101670] LIPC variants in the promoter and intron 1 modify HDL-C levels in a sex-specific fashion.
[PMID 21283740] Large-scale candidate gene analysis of HDL particle features.
Categories:
- Is a snp
- In dbSNP
- SNPs on chromosome 15
- Has genotype
- Has population
- Has Report GE
- On chip 23andMe v2
- On chip 23andMe v3
- On chip 23andMe v4
- On chip Affy GenomeWide 6
- On chip Affy500k
- On chip Ancestry v2
- On chip FTDNA2
- On chip HumanOmni1Quad
- On chip Illumina Human 1M
- On chip 23andMe v5
- On chip Ancestry v2c
- On chip Ancestry v2d