rs2891168
Orientation | plus |
Stabilized | plus |
Make rs2891168(A;A) |
Make rs2891168(A;G) |
Make rs2891168(G;G) |
Reference | GRCh38 38.1/141 |
Chromosome | 9 |
Position | 22098620 |
Gene | CDKN2B-AS1 |
is a | snp |
is | mentioned by |
dbSNP | rs2891168 |
dbSNP (classic) | rs2891168 |
ClinGen | rs2891168 |
ebi | rs2891168 |
HLI | rs2891168 |
Exac | rs2891168 |
Gnomad | rs2891168 |
Varsome | rs2891168 |
LitVar | rs2891168 |
Map | rs2891168 |
PheGenI | rs2891168 |
Biobank | rs2891168 |
1000 genomes | rs2891168 |
hgdp | rs2891168 |
ensembl | rs2891168 |
geneview | rs2891168 |
scholar | rs2891168 |
rs2891168 | |
pharmgkb | rs2891168 |
gwascentral | rs2891168 |
openSNP | rs2891168 |
23andMe | rs2891168 |
SNPshot | rs2891168 |
SNPdbe | rs2891168 |
MSV3d | rs2891168 |
GWAS Ctlg | rs2891168 |
GMAF | 0.4201 |
Max Magnitude | 0 |
? | (A;A) (A;G) (G;G) | 28 |
---|---|---|
|
Rs2891168 | |
---|---|
PubMed | [PMID 17478681] |
Affy Probeset | SNP_A-2150146 |
Affy Orientation | same |
On GW 5.0 | 1 |
Alleles A/B | A/G |
Ancestral | A |
Population | CEU |
Allele | G |
Case Freq. | |
Control Freq. | |
Odds Ratio Het | 1.30 |
Odds Ratio Hom | 1.54 |
Odds Ratio All | 1.23 |
Disease | Coronary artery disease (CAD) |
rs2891168 increases susceptibility to Coronary artery disease 1.30 times for heterozygotes (AG) and 1.54 times for homozygotes (GG) [PMID 18048406]
[PMID 19463184] Worldwide patterns of haplotype diversity at 9p21.3, a locus associated with type 2 diabetes and coronary heart disease
[PMID 20696043] Replication of the association of chromosomal region 9p21.3 with generalized aggressive periodontitis (gAgP) using an independent case-control cohort
[PMID 21949331] 44 Tiling array shows low ANRIL, high CDKN2B expression associated with chromosome 9p21 coronary artery disease (CAD) risk genotype
[PMID 18987759] Genetic testing for atherosclerosis risk: inevitability or pipe dream?
[PMID 19019192] Association of genetic variation on chromosome 9p21.3 and arterial stiffness.
[PMID 19214202] Identification of a shared genetic susceptibility locus for coronary heart disease and periodontitis.
[PMID 19578366] Variants in the CDKN2B and RTEL1 regions are associated with high-grade glioma susceptibility.
[PMID 19888323] Relationship between CAD risk genotype in the chromosome 9p21 locus and gene expression. Identification of eight new ANRIL splice variants.
[PMID 20403154] Common genetic variants on chromosome 9p21 are associated with myocardial infarction and type 2 diabetes in an Italian population.