rs3003609
From SNPedia
| Orientation | plus |
| Stabilized | plus |
| Geno | Mag | Summary |
|---|---|---|
| (C;C) | 0 | normal |
| (C;T) | ? | |
| (T;T) | associated with heavier smoking in Caucasians |
| Reference | GRCh38 38.1/141 |
| Chromosome | 9 |
| Position | 128222476 |
| Gene | DNM1 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs3003609 |
| dbSNP (classic) | rs3003609 |
| ClinGen | rs3003609 |
| ebi | rs3003609 |
| HLI | rs3003609 |
| Exac | rs3003609 |
| Gnomad | rs3003609 |
| Varsome | rs3003609 |
| LitVar | rs3003609 |
| Map | rs3003609 |
| PheGenI | rs3003609 |
| Biobank | rs3003609 |
| 1000 genomes | rs3003609 |
| hgdp | rs3003609 |
| ensembl | rs3003609 |
| geneview | rs3003609 |
| scholar | rs3003609 |
| rs3003609 | |
| pharmgkb | rs3003609 |
| gwascentral | rs3003609 |
| openSNP | rs3003609 |
| 23andMe | rs3003609 |
| SNPshot | rs3003609 |
| SNPdbe | rs3003609 |
| MSV3d | rs3003609 |
| GWAS Ctlg | rs3003609 |
| GMAF | 0.4706 |
| Max Magnitude | 0 |
| ? | (C;C) (C;T) (T;T) | 28 |
|---|---|---|
|
| ||
rs3003609 is a SNP in the dynamin 1 DNM1 gene.
The (T) allele of rs3003609 is associated with heavier smoking and thus nicotine dependence, at least in Caucasians though perhaps not African-Americans, based on a study of 600+ families.[PMID 18987626
]
| ClinVar | |
|---|---|
| Risk | Rs3003609(T;T) |
| Alt | Rs3003609(T;T) |
| Reference | Rs3003609(C;C) |
| Significance | Non-pathogenic |
| Disease | not specified |
| Variation | info |
| Gene | DNM1 |
| CLNDBN | not specified |
| Reversed | 0 |
| HGVS | NC_000009.11:g.130984755C>T |
| CLNSRC | |
| CLNACC | RCV000429521.1, |
