rs3750848
Orientation | minus |
Stabilized | minus |
Make rs3750848(A;A) |
Make rs3750848(A;C) |
Make rs3750848(C;C) |
Reference | GRCh38 38.1/142 |
Chromosome | 10 |
Position | 122455799 |
Gene | ARMS2, LOC105378525 |
is a | snp |
is | mentioned by |
dbSNP | rs3750848 |
dbSNP (classic) | rs3750848 |
ClinGen | rs3750848 |
ebi | rs3750848 |
HLI | rs3750848 |
Exac | rs3750848 |
Gnomad | rs3750848 |
Varsome | rs3750848 |
LitVar | rs3750848 |
Map | rs3750848 |
PheGenI | rs3750848 |
Biobank | rs3750848 |
1000 genomes | rs3750848 |
hgdp | rs3750848 |
ensembl | rs3750848 |
geneview | rs3750848 |
scholar | rs3750848 |
rs3750848 | |
pharmgkb | rs3750848 |
gwascentral | rs3750848 |
openSNP | rs3750848 |
23andMe | rs3750848 |
23andMe all | rs3750848 |
SNPshot | rs3750848 |
SNPdbe | rs3750848 |
MSV3d | rs3750848 |
GWAS Ctlg | rs3750848 |
GMAF | 0.2736 |
Max Magnitude | 0 |
? | (A;A) (A;C) (C;C) | 28 |
---|---|---|
|
nature age related macular degeneration is associated with five highly correlated SNPs (rs10490924, rs3750848, rs3793917, rs11200638 and rs932275; r2 < 0.88) showed strongest association with AMD (2.72 < OR < 2.86)
[PMID 19933195] Analysis of six genetic risk factors highly associated with AMD in the region surrounding ARMS2 and HTRA1 on chromosome 10q26
[PMID 21878851] ASSOCIATION BETWEEN HIGH-RISK DISEASE LOCI AND RESPONSE TO ANTI-VASCULAR ENDOTHELIAL GROWTH FACTOR TREATMENT FOR WET AGE-RELATED MACULAR DEGENERATION
[PMID 16642439] Cigarette smoking strongly modifies the association of LOC387715 and age-related macular degeneration.
[PMID 17884985] A variant of mitochondrial protein LOC387715/ARMS2, not HTRA1, is strongly associated with age-related macular degeneration.
[PMID 20140183] Genetic and functional dissection of HTRA1 and LOC387715 in age-related macular degeneration.
[PMID 20157352] Genetic analysis of typical wet-type age-related macular degeneration and polypoidal choroidal vasculopathy in Japanese population.
GWAS snp | |
---|---|
PMID | [PMID 23577725![]() |
Trait | Age-related macular degeneration (extreme sampling) |
Title | Genetic factors in nonsmokers with age-related macular degeneration revealed through genome-wide gene-environment interaction analysis. |
Risk Allele | C |
P-val | 3E-29 |
Odds Ratio | 3.12 [2.55-3.80] |