rs4140564
From SNPedia
Orientation | minus |
Stabilized | minus |
Geno | Mag | Summary |
---|---|---|
(T;T) | 0 | common in complete genomics |
Make rs4140564(C;C) |
Make rs4140564(C;T) |
Reference | GRCh38 38.1/141 |
Chromosome | 1 |
Position | 186755871 |
is a | snp |
is | mentioned by |
dbSNP | rs4140564 |
dbSNP (classic) | rs4140564 |
ClinGen | rs4140564 |
ebi | rs4140564 |
HLI | rs4140564 |
Exac | rs4140564 |
Gnomad | rs4140564 |
Varsome | rs4140564 |
LitVar | rs4140564 |
Map | rs4140564 |
PheGenI | rs4140564 |
Biobank | rs4140564 |
1000 genomes | rs4140564 |
hgdp | rs4140564 |
ensembl | rs4140564 |
geneview | rs4140564 |
scholar | rs4140564 |
rs4140564 | |
pharmgkb | rs4140564 |
gwascentral | rs4140564 |
openSNP | rs4140564 |
23andMe | rs4140564 |
SNPshot | rs4140564 |
SNPdbe | rs4140564 |
MSV3d | rs4140564 |
GWAS Ctlg | rs4140564 |
GMAF | 0.04408 |
Max Magnitude | 0 |
? | (C;C) (C;T) (T;T) | 28 |
---|---|---|
|
rs4140564, a SNP on chromosome 1 near the PTGS2 and PLA2G4A genes, has been associated with knee osteoarthritis.
A study of 255 British patients, replicated subsequently in ~2,000 UK, Dutch and US patients, found that rs4140564 was associated with knee osteoarthritis in all populations studied with an overall odds ratio = 1.55, CI: 1.30-1.85, p < 6.9 x 10e-7.[PMID 18471798]
GWAS | |
---|---|
SNP | rs4140564 |
PubMedID | [PMID 18471798] |
Condition | Knee osteoarthritis |
Gene | PTGS2, PLA2G4A |
Risk Allele | |
pValue | 3.00E-006 |
OR | 1.59 |
95% CI | 1.31-1.94 |