rs4299376

Orientation

plus

Stabilized

plus

Make rs4299376(G;G)

Make rs4299376(G;T)

Make rs4299376(T;T)

Reference

GRCh38 38.1/141

Chromosome

2

Position

43845437

Gene	ABCG8, LOC102725159

is a	snp
is	mentioned by
dbSNP	rs4299376
dbSNP (classic)	rs4299376
ClinGen	rs4299376
ebi	rs4299376
HLI	rs4299376
Exac	rs4299376
Gnomad	rs4299376
Varsome	rs4299376
LitVar	rs4299376
Map	rs4299376
PheGenI	rs4299376
Biobank	rs4299376
1000 genomes	rs4299376
hgdp	rs4299376
ensembl	rs4299376
geneview	rs4299376
scholar	rs4299376
google	rs4299376
pharmgkb	rs4299376
gwascentral	rs4299376
openSNP	rs4299376
23andMe	rs4299376
SNPshot	rs4299376
SNPdbe	rs4299376
MSV3d	rs4299376
GWAS Ctlg	rs4299376

GMAF

0.1726

Max Magnitude

0

?	(G;G) (G;T) (T;T)	28

GWAS snp
PMID	[PMID 20686565]
Trait
Title	Biological, clinical and population relevance of 95 loci for blood lipids.
Risk Allele	G
P-val	0
Odds Ratio	2.7500 None

[PMID 19060906] Common variants at 30 loci contribute to polygenic dyslipidemia.

[PMID 19913121] Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.

[PMID 23707316] High intestinal cholesterol absorption is associated with cardiovascular disease and risk alleles in ABCG8 and ABO: evidence from the LURIC and YFS cohorts and from a meta-analysis

[PMID 23100282] Impact of common genetic variation on response to simvastatin therapy among 18 705 participants in the Heart Protection Study.

GWAS snp
PMID	[PMID 24097068]
Trait	Cholesterol, total
Title	Discovery and refinement of loci associated with lipid levels.
Risk Allele	G
P-val	3E-73
Odds Ratio	.08 [NR] unit increase

[PMID 25920552] Lipids, obesity and gallbladder disease in women: insights from genetic studies using the cardiovascular gene-centric 50K SNP array

GWAS snp
PMID	[PMID 19936222]
Trait	Lipid metabolism phenotypes
Title	Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.
Risk Allele
P-val	2E-8
Odds Ratio	2.60 [NR] unit increase