rs4362
| Orientation | plus |
| Stabilized | plus |
| Geno | Mag | Summary |
|---|---|---|
| (T;T) | 0 | common in clinvar |
| Make rs4362(C;C) |
| Make rs4362(C;T) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 17 |
| Position | 63496400 |
| Gene | ACE |
| is a | snp |
| is | mentioned by |
| dbSNP | rs4362 |
| dbSNP (classic) | rs4362 |
| ClinGen | rs4362 |
| ebi | rs4362 |
| HLI | rs4362 |
| Exac | rs4362 |
| Gnomad | rs4362 |
| Varsome | rs4362 |
| LitVar | rs4362 |
| Map | rs4362 |
| PheGenI | rs4362 |
| Biobank | rs4362 |
| 1000 genomes | rs4362 |
| hgdp | rs4362 |
| ensembl | rs4362 |
| geneview | rs4362 |
| scholar | rs4362 |
| rs4362 | |
| pharmgkb | rs4362 |
| gwascentral | rs4362 |
| openSNP | rs4362 |
| 23andMe | rs4362 |
| SNPshot | rs4362 |
| SNPdbe | rs4362 |
| MSV3d | rs4362 |
| GWAS Ctlg | rs4362 |
| GMAF | 0.4408 |
| Max Magnitude | 0 |
| ? | (C;C) (C;T) (T;T) | 28 |
|---|---|---|
|
| ||
[PMID 24622918] Renin-Angiotensin System Genetic Polymorphisms and Brain White Matter Lesions in Older Australians
[PMID 18057531
] Homogeneous assay of rs4343, an ACE I/D proxy, and an analysis in the British Women's Heart and Health Study (BWHHS).
[PMID 18076107] Confronting complexity in late-onset Alzheimer disease: application of two-stage analysis approach addressing heterogeneity and epistasis.
[PMID 19105203] An association analysis of Alzheimer disease candidate genes detects an ancestral risk haplotype clade in ACE and putative multilocus association between ACE, A2M, and LRRTM3.
[PMID 19132786] Angiotensin-converting enzyme gene does not contribute to genetic susceptibility to systemic sclerosis in European Caucasians.
[PMID 20416077] Identification of type 2 diabetes-associated combination of SNPs using support vector machine.
| GWAS snp | |
|---|---|
| PMID | [PMID 24816252]
|
| Trait | Blood metabolite levels |
| Title | An atlas of genetic influences on human blood metabolites. |
| Risk Allele | T |
| P-val | 1E-21 |
| Odds Ratio | .06 [0.049-0.073] unit increase |
| ClinVar | |
|---|---|
| Risk | rs4362(C;C) |
| Alt | rs4362(C;C) |
| Reference | Rs4362(T;T) |
| Significance | Non-pathogenic |
| Disease | not specified Renal dysplasia |
| Variation | info |
| Gene | ACE |
| CLNDBN | not specified Renal dysplasia |
| Reversed | 0 |
| HGVS | NC_000017.10:g.61573761T>C |
| CLNSRC | |
| CLNACC | RCV000243922.1, RCV000342807.1, |
