Implicated as part of a haplotype of the dopamine D1 receptor DRD1 gene associated with autism spectrum disorders in families having only affected males. The haplotype is rs265981(C)-rs4532(A)-rs686(T) as published, though not necessarily as oriented in dbSNP.[PMID 18205172]
[PMID 20382433] No genetic association between dopamine D1 receptor gene and [early onset] schizophrenia
[PMID 20456319] Association of polymorphisms in the BDNF, DRD1 and DRD3 genes with tobacco smoking in schizophrenia
[PMID 22093926] [Association analysis between dopamine D1 receptor gene and symptom quantitative trait of schizophrenia]
[PMID 15087492] A new approach to SNP genotyping with fluorescently labeled mononucleotides.
[PMID 17092969] Association study of four dopamine D1 receptor gene polymorphisms and clozapine treatment response.
[PMID 18092181] Significant association of DRD1 with nicotine dependence.
[PMID 18341651] A haplotype of the DRD1 gene is associated with alcohol dependence.
[PMID 18366720] Association of dopaminergic pathway gene polymorphisms with chronic renal insufficiency among Asian Indians with type-2 diabetes.
[PMID 21181138] Analysis of genetic variations in the dopamine D1 receptor (DRD1) gene and antipsychotics-induced tardive dyskinesia in schizophrenia.
[PMID 21955727] An association study between dopamine D1 receptor gene polymorphisms and the risk of schizophrenia.
[PMID 23036699] DRD1 rs4532 polymorphism: A potential pharmacogenomic marker for treatment response to antipsychotic drugs
[PMID 25018632] Association of dopamine D1 receptor gene polymorphism with schizophrenia: a meta-analysis
[PMID 25660313] Meta-analysis of six genes (BDNF, DRD1, DRD3, DRD4, GRIN2B and MAOA) involved in neuroplasticity and the risk for alcohol dependence