rs4648022(C;T)
From SNPedia
| 0.58x reduced risk of NHL |
| Is a | genotype |
| of | rs4648022 |
| Gene | NFKB1 |
| Chromosome | 4 |
| Position | 102,575,280 |
| mentioned | by |
| Magnitude | 1.2 |
| Repute | Good |
| Geno | Mag | Summary |
|---|---|---|
| (C;C) | 0 | Normal risk for NHL. The minor, protective allele is rare. |
| (C;T) | 1.2 | 0.58x reduced risk of NHL |
| (T;T) | 1.4 | 0.47x reduced risk for NHL |
The rare minor T allele is protective for NHL in general and subtypes, with a reduction in risk of 0.58x (95% CI .40-.84) p-trend=.0037. Risk reduction is likely greater in very rare TT homozygotes.
