rs4728142
Orientation | plus |
Stabilized | plus |
Make rs4728142(A;A) |
Make rs4728142(A;G) |
Make rs4728142(G;G) |
Reference | GRCh38 38.1/141 |
Chromosome | 7 |
Position | 128933913 |
is a | snp |
is | mentioned by |
dbSNP | rs4728142 |
dbSNP (classic) | rs4728142 |
ClinGen | rs4728142 |
ebi | rs4728142 |
HLI | rs4728142 |
Exac | rs4728142 |
Gnomad | rs4728142 |
Varsome | rs4728142 |
LitVar | rs4728142 |
Map | rs4728142 |
PheGenI | rs4728142 |
Biobank | rs4728142 |
1000 genomes | rs4728142 |
hgdp | rs4728142 |
ensembl | rs4728142 |
geneview | rs4728142 |
scholar | rs4728142 |
rs4728142 | |
pharmgkb | rs4728142 |
gwascentral | rs4728142 |
openSNP | rs4728142 |
23andMe | rs4728142 |
SNPshot | rs4728142 |
SNPdbe | rs4728142 |
MSV3d | rs4728142 |
GWAS Ctlg | rs4728142 |
GMAF | 0.2961 |
Max Magnitude | 0 |
? | (A;A) (A;G) (G;G) | 28 |
---|---|---|
|
[PMID 18285424] rs4728142, rs3807306 and a 5 bp insertion-deletion linked multiple sclerosis in three populations
GWAS snp | |
---|---|
PMID | [PMID 19838193] |
Trait | Systemic lupus erythematosus |
Title | Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus |
Risk Allele | A |
P-val | 8E-19 |
Odds Ratio | 1.43 [1.32-1.54] |
GWAS snp | |
---|---|
PMID | [PMID 21297633] |
Trait | |
Title | Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47 |
Risk Allele | A |
P-val | 2E-8 |
Odds Ratio | 1.0700 [1.03-1.11] |
[PMID 21471993] Interferon regulatory factor 5 gene variants and pharmacological and clinical outcome of Interferon? therapy in multiple sclerosis
[PMID 22440820] IRF5 polymorphism predicts prognosis in patients with systemic sclerosis
[PMID 17412832] Three functional variants of IFN regulatory factor 5 (IRF5) define risk and protective haplotypes for human lupus.
[PMID 19772658] Exon expression in lymphoblastoid cell lines from subjects with schizophrenia before and after glucose deprivation.
[PMID 20169177] Genome-wide association study in Asian populations identifies variants in ETS1 and WDFY4 associated with systemic lupus erythematosus.
[PMID 20383147] Genome-wide association study of systemic sclerosis identifies CD247 as a new susceptibility locus.
[PMID 20479942] Genetic risk factors in lupus nephritis and IgA nephropathy--no support of an overlap.
[PMID 20691091] Survival dimensionality reduction (SDR): development and clinical application of an innovative approach to detect epistasis in presence of right-censored data.
[PMID 20861862] Validation of IRF5 as multiple sclerosis risk gene: putative role in interferon beta therapy and human herpes virus-6 infection.
[PMID 22257839] A two-marker haplotype in the IRF5 gene is associated with inflammatory bowel disease in a North American cohort.
[PMID 23372721] The Systemic Lupus Erythematosus IRF5 Risk Haplotype Is Associated with Systemic Sclerosis
GWAS snp | |
---|---|
PMID | [PMID 23128233] |
Trait | Ulcerative colitis |
Title | Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease. |
Risk Allele | A |
P-val | 4E-14 |
Odds Ratio | 1.10 [1.066-1.143] |
[PMID 23971939] IRF5, but not TLR4, DEFEB1, or VDR, is associated with the risk of ulcerative colitis in a Han Chinese population
[PMID 23023776] European genetic ancestry is associated with a decreased risk of lupus nephritis.
[PMID 25205108] The IRF5-TNPO3 association with systemic lupus erythematosus (SLE) has two components that other autoimmune disorders variably share
GWAS snp | |
---|---|
PMID | [PMID 24871463] |
Trait | Systemic lupus erythematosus |
Title | GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region. |
Risk Allele | A |
P-val | 7E-10 |
Odds Ratio | 1.45 [1.368-1.55] |
[PMID 25337792] Genetic association study of TNFAIP3, IFIH1, IRF5 polymorphisms with polymyositis/dermatomyositis in Chinese Han population
[PMID 26398853] Identification of Ten Additional Susceptibility Loci for Ulcerative Colitis Through Immunochip Analysis in Koreans