rs4775936
| Orientation | plus |
| Stabilized | plus |
| Make rs4775936(C;C) |
| Make rs4775936(C;T) |
| Make rs4775936(T;T) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 15 |
| Position | 51243825 |
| Gene | CYP19A1 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs4775936 |
| dbSNP (classic) | rs4775936 |
| ClinGen | rs4775936 |
| ebi | rs4775936 |
| HLI | rs4775936 |
| Exac | rs4775936 |
| Gnomad | rs4775936 |
| Varsome | rs4775936 |
| LitVar | rs4775936 |
| Map | rs4775936 |
| PheGenI | rs4775936 |
| Biobank | rs4775936 |
| 1000 genomes | rs4775936 |
| hgdp | rs4775936 |
| ensembl | rs4775936 |
| geneview | rs4775936 |
| scholar | rs4775936 |
| rs4775936 | |
| pharmgkb | rs4775936 |
| gwascentral | rs4775936 |
| openSNP | rs4775936 |
| 23andMe | rs4775936 |
| SNPshot | rs4775936 |
| SNPdbe | rs4775936 |
| MSV3d | rs4775936 |
| GWAS Ctlg | rs4775936 |
| GMAF | 0.3393 |
| Max Magnitude | 0 |
| ? | (C;C) (C;T) (T;T) | 28 |
|---|---|---|
|
| ||
[PMID 19064562
] increased risk of breast cancer with concurrent proliferative fibrocystic conditions
- rs1004982(C) 2.19 (1.24-3.85)
- rs28566535(C) 2.20 (1.27-3.82)
- rs936306(T) 1.94 (1.13-3.30)
- rs4775936(C) 1.95 (1.07-3.58)
[PMID 21442439] Single nucleotide polymorphisms of CYP19A1 predict clinical outcomes and adverse events associated with letrozole in patients with metastatic breast cancer
[PMID 22418701] Polymorphisms of CYP19A1 and response to aromatase inhibitors in metastatic breast cancer patients
[PMID 16344016] A new SNP in a negative regulatory region of the CYP19A1 gene is associated with lumbar spine BMD in postmenopausal women.
[PMID 17903296] Genome-wide association with bone mass and geometry in the Framingham Heart Study.
[PMID 18636124] Polymorphisms in the estrogen receptor 1 and vitamin C and matrix metalloproteinase gene families are associated with susceptibility to lymphoma.
[PMID 19150398] Quantitative trait loci, genes, and polymorphisms that regulate bone mineral density in mouse.
[PMID 22633539] Selected polymorphisms in sex hormone-related genes, circulating sex hormones and risk of endometrial cancer.
[PMID 23408108] Regulation of aromatase expression in breast cancer treated with anastrozole neoadjuvant therapy.
[PMID 24803183] Effects of functional genetic polymorphisms in the CYP19A1 gene on prostate cancer risk and survival
[PMID 26463708] Association of Variants in Candidate Genes with Lipid Profiles in Women with Early Breast Cancer on Adjuvant Aromatase Inhibitor Therapy
