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rs4870044

From SNPedia

Orientationplus
Stabilizedplus
Make rs4870044(C;C)
Make rs4870044(C;T)
Make rs4870044(T;T)
ReferenceGRCh38 38.1/141
Chromosome6
Position151580274
GeneCCDC170
is asnp
is mentioned by
dbSNPrs4870044
dbSNP (classic)rs4870044
ClinGenrs4870044
ebirs4870044
HLIrs4870044
Exacrs4870044
Gnomadrs4870044
Varsomers4870044
LitVarrs4870044
Maprs4870044
PheGenIrs4870044
Biobankrs4870044
1000 genomesrs4870044
hgdprs4870044
ensemblrs4870044
geneviewrs4870044
scholarrs4870044
googlers4870044
pharmgkbrs4870044
gwascentralrs4870044
openSNPrs4870044
23andMers4870044
SNPshotrs4870044
SNPdbers4870044
MSV3drs4870044
GWAS Ctlgrs4870044
GMAF0.4564
Max Magnitude0
? (C;C) (C;T) (T;T) 28


rs4870044 increases susceptibility to Bone mineral density variations, lower for carriers of the T allele [PMID 18445777]

GWAS
SNP rs4870044
PubMedID [PMID 18445777]
Condition Bone mineral density (spine)
Gene ESR1
Risk Allele T
pValue 2.00E-011
OR 0.11
95% CI 0.08-0.14) SD decreas


OMIM612114
DescBONE MINERAL DENSITY QUANTITATIVE TRAIT LOCUS 11; BMND11
Variant
Relatedalso



[PMID 22022476OA-icon.png] Common genetic variants are associated with accelerated bone mineral density loss after hematopoietic cell transplantation


[PMID 21646926] Interactions of osteoporosis candidate genes for age at menarche, age at natural menopause, and maximal height in Han Chinese women


[PMID 19181680OA-icon.png] Common variants in the region around Osterix are associated with bone mineral density and growth in childhood.


[PMID 19629617OA-icon.png] Replication study of candidate genes/loci associated with osteoporosis based on genome-wide screening.


[PMID 20072603OA-icon.png] Genome-wide association study identifies ALDH7A1 as a novel susceptibility gene for osteoporosis.



[PMID 24481879] Association of ESR1 and C6orf97 gene polymorphism with osteoporosis in postmenopausal women


[PMID 23074152OA-icon.png] Meta-analysis of genome-wide studies identifies WNT16 and ESR1 SNPs associated with bone mineral density in premenopausal women.


[PMID 28253304OA-icon.png] Bone mineral density is associated with vitamin D related rs6013897 and estrogen receptor polymorphism rs4870044: The Tromsø study.