rs5067
From SNPedia
| Orientation | plus |
| Stabilized | plus |
| Geno | Mag | Summary |
|---|---|---|
| (A;A) | 0 | normal |
| (A;G) | 0.5x reduced risk for asthma | |
| (G;G) | 0.5x reduced risk for asthma |
| Reference | GRCh38 38.1/141 |
| Chromosome | 1 |
| Position | 11845924 |
| Gene | NPPA, NPPA-AS1 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs5067 |
| dbSNP (classic) | rs5067 |
| ClinGen | rs5067 |
| ebi | rs5067 |
| HLI | rs5067 |
| Exac | rs5067 |
| Gnomad | rs5067 |
| Varsome | rs5067 |
| LitVar | rs5067 |
| Map | rs5067 |
| PheGenI | rs5067 |
| Biobank | rs5067 |
| 1000 genomes | rs5067 |
| hgdp | rs5067 |
| ensembl | rs5067 |
| geneview | rs5067 |
| scholar | rs5067 |
| rs5067 | |
| pharmgkb | rs5067 |
| gwascentral | rs5067 |
| openSNP | rs5067 |
| 23andMe | rs5067 |
| SNPshot | rs5067 |
| SNPdbe | rs5067 |
| MSV3d | rs5067 |
| GWAS Ctlg | rs5067 |
| GMAF | 0.1396 |
| Max Magnitude | 0 |
| ? | (A;A) (A;G) (G;G) | 28 |
|---|---|---|
|
| ||
rs5067 is a SNP in the natriuretic peptide precursor A NPPA gene.
In a study of ~500 asthma patients, rs5067(G) were at reduced (50% or 76%) risk; the odds ratio in the first and second populations were 0.5 (CI: 0.29-0.84, p=0.009) and 0.24 (CI: 0.11-0.53, p<0.0001), respectively. The population-attributable risk for asthma in carriers of the rs5067(G) allele was 23.3%.[PMID 18294255]
