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rs541941351

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(T;T) 0 common/normal
Make rs541941351(A;A)
Make rs541941351(A;T)
ReferenceGRCh38.p7 38.3/150
Chromosome2
Position24918797
GeneADCY3
is asnp
is mentioned by
dbSNPrs541941351
dbSNP (classic)rs541941351
ClinGenrs541941351
ebirs541941351
HLIrs541941351
Exacrs541941351
Gnomadrs541941351
Varsomers541941351
LitVarrs541941351
Maprs541941351
PheGenIrs541941351
Biobankrs541941351
1000 genomesrs541941351
hgdprs541941351
ensemblrs541941351
geneviewrs541941351
scholarrs541941351
googlers541941351
pharmgkbrs541941351
gwascentralrs541941351
openSNPrs541941351
23andMers541941351
23andMe allrs541941351
SNPshotrs541941351
SNPdbers541941351
MSV3drs541941351
GWAS Ctlgrs541941351
Max Magnitude0

rs541941351, also known as c.191A>T or p.Asn64Ile, represents a rare variant in the ADCY3 gene. It has been reported as potentially causing obesity when inherited recessively, but heterozygotes may be affected to a lesser degree, if this variant is driving related GWAS findings.[PMID 29311637]

Be aware of orientation & ambiguous flip issues due to the A/T nature of this variant and the reverse orientation of the gene.