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rs651821

From SNPedia

Orientationplus
Stabilizedplus
Make rs651821(C;C)
Make rs651821(C;T)
Make rs651821(T;T)
ReferenceGRCh38.p2 38.2/146
Chromosome11
Position116791863
GeneAPOA5
is asnp
is mentioned by
dbSNPrs651821
dbSNP (classic)rs651821
ClinGenrs651821
ebirs651821
HLIrs651821
Exacrs651821
Gnomadrs651821
Varsomers651821
LitVarrs651821
Maprs651821
PheGenIrs651821
Biobankrs651821
1000 genomesrs651821
hgdprs651821
ensemblrs651821
geneviewrs651821
scholarrs651821
googlers651821
pharmgkbrs651821
gwascentralrs651821
openSNPrs651821
23andMers651821
SNPshotrs651821
SNPdbers651821
MSV3drs651821
GWAS Ctlgrs651821
GMAF0.1589
Max Magnitude0
? (C;C) (C;T) (T;T) 28


[PMID 19732897] Associations of polymorphisms in the apolipoprotein A1/C3/A4/A5 gene cluster with familial combined hyperlipidaemia in Hong Kong Chinese


[PMID 20395964] Different effects of apolipoprotein A5 SNPs and haplotypes on triglyceride concentration in three ethnic origins

GWAS snp
PMID [PMID 22171074]
Trait
Title A genome-wide association and gene-environment interaction study for serum triglycerides levels in a healthy Chinese male population.
Risk Allele
P-val 9E-26
Odds Ratio None None


[PMID 21889769OA-icon.png] Variants in the APOA5 gene region and the response to combination therapy with statins and fenofibric acid in a randomized clinical trial of individuals with mixed dyslipidemia


[PMID 21375366] Impact of apolipoprotein A5 (APOA5) polymorphisms on serum triglyceride levels in schizophrenic patients under long-term atypical antipsychotic treatment

GWAS snp
PMID [PMID 22286219OA-icon.png]
Trait
Title Genome-wide association study identifies multiple loci influencing human serum metabolite levels.
Risk Allele
P-val 8E-20
Odds Ratio 0.2700 None


[PMID 17357073OA-icon.png] Genetic analysis of 103 candidate genes for coronary artery disease and associated phenotypes in a founder population reveals a new association between endothelin-1 and high-density lipoprotein cholesterol.


[PMID 17357083OA-icon.png] Medical sequencing at the extremes of human body mass.


[PMID 18078817OA-icon.png] Multiple genetic determinants of plasma lipid levels in Caribbean Hispanics.


[PMID 18196181OA-icon.png] Correction of population stratification in large multi-ethnic association studies.


[PMID 18441017OA-icon.png] An apolipoprotein A-V gene SNP is associated with marked hypertriglyceridemia among Asian-American patients.


[PMID 19041386OA-icon.png] Genetic-epidemiological evidence on genes associated with HDL cholesterol levels: a systematic in-depth review.


[PMID 19299407OA-icon.png] Replication of genetic associations with plasma lipoprotein traits in a multiethnic sample.


[PMID 19913121OA-icon.png] Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.


[PMID 20452521OA-icon.png] Triglyceride-mediated pathways and coronary disease: collaborative analysis of 101 studies.


[PMID 20570915] Genetic determinants of major blood lipids in Pakistanis compared with Europeans.

GWAS snp
PMID [PMID 24386095OA-icon.png]
Trait Lipid traits
Title A genome wide association study identifies common variants associated with lipid levels in the Chinese population.
Risk Allele C
P-val 2E-59
Odds Ratio .17 [0.14-0.20] mmol/L increase


[PMID 26824674OA-icon.png] Interactions of Environmental Factors and APOA1-APOC3-APOA4-APOA5 Gene Cluster Gene Polymorphisms with Metabolic Syndrome.


[PMID 28624160] Association of apolipoprotein A5 gene variants with metabolic syndrome in Tunisian population.


[PMID 29866721OA-icon.png] Effects of polymorphisms in APOA5 on the plasma levels of triglycerides and risk of coronary heart disease in Jilin, northeast China: a case-control study.


[PMID 30929539] APOA5 rs651821 confers increased risk for hypertension in Tongdao Dong population.


[PMID 31544728] Carbohydrate and sodium intake and physical activity interact with genetic risk scores of four genetic variants mainly related to lipid metabolism to modulate metabolic syndrome risk in Korean middle-aged adults.