rs651821
| Orientation | plus |
| Stabilized | plus |
| Make rs651821(C;C) |
| Make rs651821(C;T) |
| Make rs651821(T;T) |
| Reference | GRCh38.p2 38.2/146 |
| Chromosome | 11 |
| Position | 116791863 |
| Gene | APOA5 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs651821 |
| dbSNP (classic) | rs651821 |
| ClinGen | rs651821 |
| ebi | rs651821 |
| HLI | rs651821 |
| Exac | rs651821 |
| Gnomad | rs651821 |
| Varsome | rs651821 |
| LitVar | rs651821 |
| Map | rs651821 |
| PheGenI | rs651821 |
| Biobank | rs651821 |
| 1000 genomes | rs651821 |
| hgdp | rs651821 |
| ensembl | rs651821 |
| geneview | rs651821 |
| scholar | rs651821 |
| rs651821 | |
| pharmgkb | rs651821 |
| gwascentral | rs651821 |
| openSNP | rs651821 |
| 23andMe | rs651821 |
| SNPshot | rs651821 |
| SNPdbe | rs651821 |
| MSV3d | rs651821 |
| GWAS Ctlg | rs651821 |
| GMAF | 0.1589 |
| Max Magnitude | 0 |
| ? | (C;C) (C;T) (T;T) | 28 |
|---|---|---|
|
| ||
[PMID 19732897] Associations of polymorphisms in the apolipoprotein A1/C3/A4/A5 gene cluster with familial combined hyperlipidaemia in Hong Kong Chinese
[PMID 20395964] Different effects of apolipoprotein A5 SNPs and haplotypes on triglyceride concentration in three ethnic origins
| GWAS snp | |
|---|---|
| PMID | [PMID 22171074] |
| Trait | |
| Title | A genome-wide association and gene-environment interaction study for serum triglycerides levels in a healthy Chinese male population. |
| Risk Allele | |
| P-val | 9E-26 |
| Odds Ratio | None None |
[PMID 21889769
] Variants in the APOA5 gene region and the response to combination therapy with statins and fenofibric acid in a randomized clinical trial of individuals with mixed dyslipidemia
[PMID 21375366] Impact of apolipoprotein A5 (APOA5) polymorphisms on serum triglyceride levels in schizophrenic patients under long-term atypical antipsychotic treatment
| GWAS snp | |
|---|---|
| PMID | [PMID 22286219]
|
| Trait | |
| Title | Genome-wide association study identifies multiple loci influencing human serum metabolite levels. |
| Risk Allele | |
| P-val | 8E-20 |
| Odds Ratio | 0.2700 None |
[PMID 17357073] Genetic analysis of 103 candidate genes for coronary artery disease and associated phenotypes in a founder population reveals a new association between endothelin-1 and high-density lipoprotein cholesterol.
[PMID 17357083] Medical sequencing at the extremes of human body mass.
[PMID 18078817] Multiple genetic determinants of plasma lipid levels in Caribbean Hispanics.
[PMID 18196181] Correction of population stratification in large multi-ethnic association studies.
[PMID 18441017] An apolipoprotein A-V gene SNP is associated with marked hypertriglyceridemia among Asian-American patients.
[PMID 19041386] Genetic-epidemiological evidence on genes associated with HDL cholesterol levels: a systematic in-depth review.
[PMID 19299407] Replication of genetic associations with plasma lipoprotein traits in a multiethnic sample.
[PMID 19913121] Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.
[PMID 20452521] Triglyceride-mediated pathways and coronary disease: collaborative analysis of 101 studies.
[PMID 20570915] Genetic determinants of major blood lipids in Pakistanis compared with Europeans.
| GWAS snp | |
|---|---|
| PMID | [PMID 24386095]
|
| Trait | Lipid traits |
| Title | A genome wide association study identifies common variants associated with lipid levels in the Chinese population. |
| Risk Allele | C |
| P-val | 2E-59 |
| Odds Ratio | .17 [0.14-0.20] mmol/L increase |
[PMID 26824674] Interactions of Environmental Factors and APOA1-APOC3-APOA4-APOA5 Gene Cluster Gene Polymorphisms with Metabolic Syndrome.
[PMID 28624160] Association of apolipoprotein A5 gene variants with metabolic syndrome in Tunisian population.
[PMID 29866721] Effects of polymorphisms in APOA5 on the plasma levels of triglycerides and risk of coronary heart disease in Jilin, northeast China: a case-control study.
[PMID 30929539] APOA5 rs651821 confers increased risk for hypertension in Tongdao Dong population.
[PMID 31544728] Carbohydrate and sodium intake and physical activity interact with genetic risk scores of four genetic variants mainly related to lipid metabolism to modulate metabolic syndrome risk in Korean middle-aged adults.
