rs6596075

plus

Geno	Mag	Summary
(C;C)		2x risk of Crohn's disease
(C;G)		1.5x risk
(G;G)		normal

Reference

GRCh38 38.1/141

Chromosome

5

Position

132406536

Gene

IBD5

is a	snp
is	mentioned by
dbSNP	rs6596075
dbSNP (classic)	rs6596075
ClinGen	rs6596075
ebi	rs6596075
HLI	rs6596075
Exac	rs6596075
Gnomad	rs6596075
Varsome	rs6596075
LitVar	rs6596075
Map	rs6596075
PheGenI	rs6596075
Biobank	rs6596075
1000 genomes	rs6596075
hgdp	rs6596075
ensembl	rs6596075
geneview	rs6596075
scholar	rs6596075
google	rs6596075
pharmgkb	rs6596075
gwascentral	rs6596075
openSNP	rs6596075
23andMe	rs6596075
SNPshot	rs6596075
SNPdbe	rs6596075
MSV3d	rs6596075
GWAS Ctlg	rs6596075

GMAF

0.2452

Max Magnitude

0

?

(C;C) (C;G) (G;G)

28

rs6596075 has been reported in a large study to be associated with Crohn's disease.

The risk allele (oriented to the dbSNP entry) is (C); the odds ratio associated with heterozygotes is 1.55 (CI 1.00-2.39), and for homozygotes, 2.06 (CI 1.35-3.14). [PMID 17554300 ]

OMIM	606348
Desc	INFLAMMATORY BOWEL DISEASE 5; IBD5
Variant
Related	also

[PMID 21061378] Two independent genetic factors responsible for the associations of the IBD5 locus with Crohn's disease in the Czech population

[PMID 21674708] Two independent genetic factors responsible for the associations of the IBD5 locus with Crohn's disease in the Czech population

[PMID 18614543 ] The 5q31 variants associated with psoriasis and Crohn's disease are distinct.

[PMID 18853133 ] Gene variants influencing measures of inflammation or predisposing to autoimmune and inflammatory diseases are not associated with the risk of type 2 diabetes.