| Geno
|
Mag
|
Summary
|
| (G;G)
|
2
|
>2.74x increased risk of developing schizophrenia
|
| (G;T)
|
2
|
2.74x increased risk of developing schizophrenia
|
| (T;T)
|
1
|
Normal risk of developing schizophrenia
|
This snp is in the Pseudoautosomal region.
rs6603272, part of a haplotype block spanning introns 4, 5 and 6 of the IL3RA gene, has been reported in a whole genome association study to be associated with schizophrenia. (The other SNPs in this block are rs6422441 and rs17883192.)
The risk allele (oriented to the dbSNP entry) is (G); the odds ratio associated with this allele is 2.74. [PMID 17522711]
[PMID 19281803] A family-based study of the IL3RA gene on susceptibility to schizophrenia in a Chinese Han population
[PMID 18547720] Association between interleukin-3 receptor alpha polymorphism and schizophrenia in the Chinese population.
