rs7250581
From SNPedia
| Orientation | plus |
| Stabilized | plus |
| Geno | Mag | Summary |
|---|---|---|
| (A;A) | normal | |
| (A;G) | 0 | normal |
| (G;G) | 2 | 1.4x risk |
| Reference | GRCh38 38.1/141 |
| Chromosome | 19 |
| Position | 29573489 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs7250581 |
| dbSNP (classic) | rs7250581 |
| ClinGen | rs7250581 |
| ebi | rs7250581 |
| HLI | rs7250581 |
| Exac | rs7250581 |
| Gnomad | rs7250581 |
| Varsome | rs7250581 |
| LitVar | rs7250581 |
| Map | rs7250581 |
| PheGenI | rs7250581 |
| Biobank | rs7250581 |
| 1000 genomes | rs7250581 |
| hgdp | rs7250581 |
| ensembl | rs7250581 |
| geneview | rs7250581 |
| scholar | rs7250581 |
| rs7250581 | |
| pharmgkb | rs7250581 |
| gwascentral | rs7250581 |
| openSNP | rs7250581 |
| 23andMe | rs7250581 |
| SNPshot | rs7250581 |
| SNPdbe | rs7250581 |
| MSV3d | rs7250581 |
| GWAS Ctlg | rs7250581 |
| GMAF | 0.07668 |
| Max Magnitude | 2 |
| ? | (A;A) (A;G) (G;G) | 28 |
|---|---|---|
|
| ||
rs7250581 has been reported in a large study to be associated with heart disease, in particular, coronary artery disease.
The risk allele (oriented to the dbSNP entry) is (G); the odds ratio associated with heterozygotes is 1.06 (CI 0.79-1.43), and for homozygotes, 1.40 (CI 1.05-1.86). [PMID 17554300
]
[PMID 19955471] Genetic Variants Identified in a European Genome-Wide Association Study That Were Found to Predict Incident Coronary Heart Disease in the Atherosclerosis Risk in Communities Study
[PMID 19956433] Genetics of coronary artery disease: focus on genome-wide association studies.
