rs72558189
From SNPedia
Warfarin (Coumadin®) |
Orientation | plus |
Stabilized | plus |
Geno | Mag | Summary |
---|---|---|
(A;A) | 2.5 | CYP2C9*14 homozygote |
(A;G) | carrier of one CYP2C9*14 allele | |
(G;G) | 0 | normal |
Reference | GRCh38 38.1/141 |
Chromosome | 10 |
Position | 94942234 |
Gene | CYP2C9 |
is a | snp |
is | mentioned by |
dbSNP | rs72558189 |
dbSNP (classic) | rs72558189 |
ClinGen | rs72558189 |
ebi | rs72558189 |
HLI | rs72558189 |
Exac | rs72558189 |
Gnomad | rs72558189 |
Varsome | rs72558189 |
LitVar | rs72558189 |
Map | rs72558189 |
PheGenI | rs72558189 |
Biobank | rs72558189 |
1000 genomes | rs72558189 |
hgdp | rs72558189 |
ensembl | rs72558189 |
geneview | rs72558189 |
scholar | rs72558189 |
rs72558189 | |
pharmgkb | rs72558189 |
gwascentral | rs72558189 |
openSNP | rs72558189 |
23andMe | rs72558189 |
SNPshot | rs72558189 |
SNPdbe | rs72558189 |
MSV3d | rs72558189 |
GWAS Ctlg | rs72558189 |
Max Magnitude | 2.5 |
This SNP has been recognized by the Coriell Personalized Medicine Collaborative ICOB.
|
rs72558189, also known as 374G>A, 3552G>A or R125H, is a SNP in the CYP2C9 gene.
The rs72558189(A) allele defines the CYP2C9*14 variant, which may have decreased activity.
ClinVar | |
---|---|
Risk | Rs72558189(A;A) |
Alt | Rs72558189(A;A) |
Reference | Rs72558189(G;G) |
Significance | Untested |
Disease | |
Variation | info |
Gene | CYP2C9 |
CLNDBN | |
Reversed | 0 |
HGVS | NC_000010.10:g.96701991G>A |
CLNSRC | |
CLNACC |
[PMID 15371982] Novel CYP2C9 genetic variants in Asian subjects and their influence on maintenance warfarin dose.
[PMID 16099926] Functional characterization of novel allelic variants of CYP2C9 recently discovered in southeast Asians.