rs7569963
From SNPedia
Orientation | plus |
Stabilized | plus |
Geno | Mag | Summary |
---|---|---|
(G;G) | 0 |
Make rs7569963(A;A) |
Make rs7569963(A;G) |
Reference | GRCh38 38.1/141 |
Chromosome | 2 |
Position | 207608460 |
Gene | METTL21A |
is a | snp |
is | mentioned by |
dbSNP | rs7569963 |
dbSNP (classic) | rs7569963 |
ClinGen | rs7569963 |
ebi | rs7569963 |
HLI | rs7569963 |
Exac | rs7569963 |
Gnomad | rs7569963 |
Varsome | rs7569963 |
LitVar | rs7569963 |
Map | rs7569963 |
PheGenI | rs7569963 |
Biobank | rs7569963 |
1000 genomes | rs7569963 |
hgdp | rs7569963 |
ensembl | rs7569963 |
geneview | rs7569963 |
scholar | rs7569963 |
rs7569963 | |
pharmgkb | rs7569963 |
gwascentral | rs7569963 |
openSNP | rs7569963 |
23andMe | rs7569963 |
SNPshot | rs7569963 |
SNPdbe | rs7569963 |
MSV3d | rs7569963 |
GWAS Ctlg | rs7569963 |
GMAF | 0.1809 |
Max Magnitude | 0 |
? | (A;A) (A;G) (G;G) | 28 |
---|---|---|
|
rs7569963 is directly adjacent to CREB1.
[PMID 17548750] Associated with significantly (p = 0.005) increased chance of suicide in a study of 1447 citalopram users (male only subgroup, 539 in total). Two haplotypes (see below) also showed significant association with suicidality in the male subgroup.
- rs2709376(C),rs2253206(A),rs7569963(A),rs7594560(T),rs4675690(C) - common haplotype, reduced chance of suicide in males, p = 0.004
- rs2709376(C),rs2253206(A),rs7569963(G),rs7594560(T),rs4675690(T) - increased chance of suicide in males, p = 0.009
[PMID 20643483] A preliminary investigation of the influence of CREB1 gene on treatment resistance in major depression.