rs7679

Orientation

plus

Stabilized

plus

Geno	Mag	Summary
(T;T)	0	common on affy axiom data

Make rs7679(C;C)

Make rs7679(C;T)

Reference

GRCh38 38.1/141

Chromosome

20

Position

45947863

Gene

PCIF1

is a	snp
is	mentioned by
dbSNP	rs7679
dbSNP (classic)	rs7679
ClinGen	rs7679
ebi	rs7679
HLI	rs7679
Exac	rs7679
Gnomad	rs7679
Varsome	rs7679
LitVar	rs7679
Map	rs7679
PheGenI	rs7679
Biobank	rs7679
1000 genomes	rs7679
hgdp	rs7679
ensembl	rs7679
geneview	rs7679
scholar	rs7679
google	rs7679
pharmgkb	rs7679
gwascentral	rs7679
openSNP	rs7679
23andMe	rs7679
23andMe all	rs7679
SNPshot	rs7679
SNPdbe	rs7679
MSV3d	rs7679
GWAS Ctlg	rs7679

GMAF

0.1006

Max Magnitude

0

?	(C;C) (C;T) (T;T)	28

per the 23andMe blog, the minor allele of this SNP (C) was associated with decreased HDL cholesterol and increased triglycerides

SNP	Rarer allele	LDL	HDL	TG
rs6544713	T	+
rs2650000	A	+
rs471364	C		-
rs1800961	T		-
rs7679	C		-	+
rs2967605	T		-
rs2409722	T			-
rs10903129	A	-	-	-
rs6756629	A	-	+	-
rs12670798	C	+	+	+
rs7395662	A	-	+	+
rs174570	T	-	-	+
rs2271293	A	-	+	-
rs2624265	C			+
rs2167079	T		+
rs9891572	T		+
rs4844614	T	+
rs5031002	G	+

GWAS snp
PMID	[PMID 19060906]
Trait	HDL cholesterol
Title	Common variants at 30 loci contribute to polygenic dyslipidemia
Risk Allele	C
P-val	4E-9
Odds Ratio	0.07 [0.03-0.11] SD decrease

[PMID 19951432] Analysis of recently identified dyslipidemia alleles reveals two loci that contribute to risk for carotid artery disease.

[PMID 20160193] Investigation of variants identified in caucasian genome-wide association studies for plasma high-density lipoprotein cholesterol and triglycerides levels in Mexican dyslipidemic study samples.

[PMID 20385826] Genome-wide association study of advanced age-related macular degeneration identifies a role of the hepatic lipase gene (LIPC).

[PMID 21347282] Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project.