rs80357805

minus

Geno	Mag	Summary
(-;GA)	6	Likely miscall in Ancestry data; otherwise, BRCA1 variant considered pathogenic for breast cancer
(GA;GA)	0	common in clinvar

Make rs80357805(-;-)

Reference

GRCh38 38.1/141

Chromosome

17

Position

43091888

Gene

BRCA1

is a	snp
is	mentioned by
dbSNP	rs80357805
dbSNP (classic)	rs80357805
ClinGen	rs80357805
ebi	rs80357805
HLI	rs80357805
Exac	rs80357805
Gnomad	rs80357805
Varsome	rs80357805
LitVar	rs80357805
Map	rs80357805
PheGenI	rs80357805
Biobank	rs80357805
1000 genomes	rs80357805
hgdp	rs80357805
ensembl	rs80357805
geneview	rs80357805
scholar	rs80357805
google	rs80357805
pharmgkb	rs80357805
gwascentral	rs80357805
openSNP	rs80357805
23andMe	rs80357805
SNPshot	rs80357805
SNPdbe	rs80357805
MSV3d	rs80357805
GWAS Ctlg	rs80357805

Max Magnitude

6

rs80357805, also known as 3761delGA, c.3642_3643delGA and p.Glu1214_Asn1215GluLeufs, is a variant in the BRCA1 gene considered pathogenic for breast cancer in ClinVar.

ClinVar
Risk	rs80357805(-;-)
Alt	rs80357805(-;-)
Reference	Rs80357805(GA;GA)
Significance	Pathogenic
Disease	Familial cancer of breast Breast-ovarian cancer Hereditary cancer-predisposing syndrome
Variation	info
Gene	BRCA1
CLNDBN	Familial cancer of breast Breast-ovarian cancer, familial 1 Hereditary cancer-predisposing syndrome
Reversed	1
HGVS	NC_000017.10:g.41243905_41243906delTC
CLNSRC	Breast Cancer Information Core (BRCA1)
CLNACC	RCV000048268.2, RCV000112144.3, RCV000215002.1,