rs80357928

minus

Geno	Mag	Summary
(-;-)	0	common in clinvar
(-;T)	6	BRCA1 variant considered pathogenic for breast cancer
(-;TT)	6	BRCA1 variant considered pathogenic for breast cancer

Make rs80357928(TT;TT)

Reference

GRCh38 38.1/141

Chromosome

17

Position

43091769

Gene

BRCA1

is a	snp
is	mentioned by
dbSNP	rs80357928
dbSNP (classic)	rs80357928
ClinGen	rs80357928
ebi	rs80357928
HLI	rs80357928
Exac	rs80357928
Gnomad	rs80357928
Varsome	rs80357928
LitVar	rs80357928
Map	rs80357928
PheGenI	rs80357928
Biobank	rs80357928
1000 genomes	rs80357928
hgdp	rs80357928
ensembl	rs80357928
geneview	rs80357928
scholar	rs80357928
google	rs80357928
pharmgkb	rs80357928
gwascentral	rs80357928
openSNP	rs80357928
23andMe	rs80357928
SNPshot	rs80357928
SNPdbe	rs80357928
MSV3d	rs80357928
GWAS Ctlg	rs80357928

Max Magnitude

6

rs80357928, also known as 3880insTT, c.3761_3762insTT and p.Lys1254?fs, is a variant in the BRCA1 gene considered pathogenic for breast cancer in ClinVar.

ClinVar
Risk	rs80357928(TT;TT)
Alt	rs80357928(TT;TT)
Reference	Rs80357928(-;-)
Significance	Pathogenic
Disease	Breast-ovarian cancer Hereditary breast and ovarian cancer syndrome Hereditary cancer-predisposing syndrome
Variation	info
Gene	BRCA1
CLNDBN	Breast-ovarian cancer, familial 1 Hereditary breast and ovarian cancer syndrome Hereditary cancer-predisposing syndrome
Reversed	1
HGVS	NC_000017.10:g.41243786_41243787insAA
CLNSRC	Breast Cancer Information Core (BRCA1)
CLNACC	RCV000077131.6, RCV000123274.1, RCV000218701.1,